2020
Looking beyond the ovary for oncofertility care in women: uterine injury as a potential target for fertility-preserving treatments
Garg D, Johnstone E, Lomo L, Fair D, Rosen M, Taylor R, Silver B, Letourneau J. Looking beyond the ovary for oncofertility care in women: uterine injury as a potential target for fertility-preserving treatments. Journal Of Assisted Reproduction And Genetics 2020, 37: 1467-1476. PMID: 32342270, PMCID: PMC7311602, DOI: 10.1007/s10815-020-01792-9.Peer-Reviewed Original ResearchConceptsCancer survivorsPregnancy complicationsObstetrical outcomesFertility-preserving treatmentLow birth weightPoor obstetrical outcomesFemale cancer survivorsImpact of chemotherapyEarly pregnancy lossOncofertility carePregnancy implantationLate complicationsPregnancy outcomesPreterm birthRadiation fibrosisEndometrial receptivityGonadotoxic effectsUterine injuryBirth weightPregnancy lossPregnant uterusBlood supplyUterine functionChemotherapyComplications
2007
A novel xenograft model to test the ovarian toxicity of chemotherapy agents in women
Oktay K, Oktem O. A novel xenograft model to test the ovarian toxicity of chemotherapy agents in women. Journal Of Clinical Oncology 2007, 25: 19504-19504. DOI: 10.1200/jco.2007.25.18_suppl.19504.Peer-Reviewed Original ResearchXenograft modelFollicle lossClinical trialsChemotherapy agentsHuman ovarian xenograft modelPrimordial follicle countsNovel xenograft modelOvarian xenograft modelOvarian reserveFollicle countMice 12Ovarian toxicityCY injectionGonadotoxic effectsPremenopausal femalesSingle doseHuman ovaryOvarian piecesClinical studiesImmunodeficient miceSingle injectionNew agentsOvarian histologyXenograft vasculatureTUNEL staining
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