2008
Tests for gene‐environment interaction from case‐control data: a novel study of type I error, power and designs
Mukherjee B, Ahn J, Gruber S, Rennert G, Moreno V, Chatterjee N. Tests for gene‐environment interaction from case‐control data: a novel study of type I error, power and designs. Genetic Epidemiology 2008, 32: 615-626. PMID: 18473390, DOI: 10.1002/gepi.20337.Peer-Reviewed Original ResearchConceptsGene-environment independence assumptionCase-control studyGene-environment interactionsGene-environment associationsCase-onlyCase-control study of colorectal cancerDetection of gene-environment interactionsType I errorGene-environment dependenceStudy of colorectal cancerGene-environment independenceEffect of genetic susceptibilityCase-only methodCase-only estimatorCase-control estimatorsCase-control dataGene-environment effectsCase-control designCase-control methodCase-control analysisGlutathione S-transferase M1Empirical-BayesEpidemiological researchCase-controlColorectal cancer
2003
Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk
Zheng T, Holford T, Zahm S, Owens P, Boyle P, Zhang Y, Zhang B, Wise J, Stephenson L, Ali-Osman F. Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk. British Journal Of Cancer 2003, 88: 58-62. PMID: 12556960, PMCID: PMC2376773, DOI: 10.1038/sj.bjc.6600708.Peer-Reviewed Original ResearchConceptsBreast cancer riskGSTT1 null genotypeCancer riskAlcohol consumptionGST genotypesBreast cancerPostmenopausal womenGenetic polymorphismsIncident breast cancer patientsGlutathione S-transferase M1Breast cancer patientsT1 genetic polymorphismsCase-control studyGSTT1 genetic polymorphismsGlutathione S-transferaseS-transferase M1Cancer patientsEffect modificationGSTM1 genotypeHigh riskNew Haven CountyYounger ageCancerWomenRisk
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