2023
Surgical treatment of stage IV gastroenteropancreatic neuroendocrine carcinoma: Experience and outcomes in the United States
Kerekes D, Frey A, Bakkila B, Kunstman J, Khan S. Surgical treatment of stage IV gastroenteropancreatic neuroendocrine carcinoma: Experience and outcomes in the United States. Journal Of Surgical Oncology 2023, 128: 790-802. PMID: 37435780, DOI: 10.1002/jso.27392.Peer-Reviewed Original ResearchConceptsGastroenteropancreatic neuroendocrine carcinomasGEP-NECSingle-site surgeryOverall survivalSurgical treatmentNeuroendocrine carcinomaMortality reductionSite surgeryPrimary siteNational Cancer DatabaseRetrospective cohort studyPrimary tumor typeSurgical resectionCohort studyAggressive diseaseSurgical interventionSurvival outcomesTreatment optionsCancer DatabaseSurgeryPatientsTumor typesNECStrongest predictorCarcinoma
2014
Gastroenteropancreatic high‐grade neuroendocrine carcinoma
Sorbye H, Strosberg J, Baudin E, Klimstra D, Yao J. Gastroenteropancreatic high‐grade neuroendocrine carcinoma. Cancer 2014, 120: 2814-2823. PMID: 24771552, DOI: 10.1002/cncr.28721.Peer-Reviewed Original ResearchConceptsPlatinum-based chemotherapyNeuroendocrine carcinomaGEP-NECKi-67High-grade neuroendocrine carcinomaKi-67 proliferation indexCell neuroendocrine carcinomaSmall cell carcinomaGastroenteropancreatic (GEPHigh-grade tumorsKi-67 indexProliferation rateLong-term survivalIntermediate-gradeLocalized diseaseNeuroendocrine neoplasmsPrognostic stratificationCell carcinomaProliferation indexTreatment optionsOptimal treatmentLow-gradeTumorChemotherapyPatients
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