Family history of cancer, body weight, and p53 nuclear overexpression in Duke's C colorectal cancer
Zhang Z, Zeng Z, Sarkis A, Klimstra D, Charytonowicz E, Pollack D, Vena J, Guillem J, Marshall J, Cordon-Cardo C, Cohen A, Begg C. Family history of cancer, body weight, and p53 nuclear overexpression in Duke's C colorectal cancer. British Journal Of Cancer 1995, 71: 888-893. PMID: 7710960, PMCID: PMC2033726, DOI: 10.1038/bjc.1995.171.Peer-Reviewed Original ResearchConceptsFamily history of cancerHistory of cancerOdds ratioGenetic predisposition to colorectal cancerPredisposition to colorectal cancerFamily historyOccupational physical activityColorectal cancerMemorial Sloan-Kettering Cancer CenterDukes' C colorectal cancerFirst-degree relativesP53 overexpressionPhysical activityC colorectal cancerLowest quartileAetiological pathwaysCancer CenterAetiological heterogeneityQuartileP53-positive phenotypeP53 nuclear overexpressionMonoclonal antibody PAbBody weightP53 positivityTP53 mutations
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