2024
Effect of Incomplete Cryoablation and Matrix Metalloproteinase Inhibition on Intratumoral CD8+ T-Cell Infiltration in Murine Hepatocellular Carcinoma.
Shewarega A, Santana J, Nam D, Berz A, Tefera J, Kahl V, Mishra S, Coman D, Duncan J, Roberts S, Wetter A, Madoff D, Chapiro J. Effect of Incomplete Cryoablation and Matrix Metalloproteinase Inhibition on Intratumoral CD8+ T-Cell Infiltration in Murine Hepatocellular Carcinoma. Radiology 2024, 310: e232365. PMID: 38349244, PMCID: PMC10902598, DOI: 10.1148/radiol.232365.Peer-Reviewed Original ResearchConceptsT cell infiltrationCD8<sup>+</sup> T cellsMatrix metalloproteinase inhibitionT cellsHepatocellular carcinomaMatrix metalloproteinase inhibitorsMatrix metalloproteinasesResidual tumorCXCR3<sup>+</sup> CD8<sup>+</sup> T cellsCytotoxic CD8<sup>+</sup> T cell infiltrationIntratumoral CD8+ T cell infiltrationCD8+ T cell infiltrationCD8<sup>+</sup> T cell infiltrationMouse model of hepatocellular carcinomaEarly-stage hepatocellular carcinomaImage-guided tumor ablationUnpaired Student's <i>t</i> testModel of hepatocellular carcinomaFirst-line therapyMurine hepatocellular carcinomaT cell subsetsTumor-associated macrophagesMurine HCC modelLocal immune responseFemale BALB/c mice
2021
P–273 Effects of ovulation induction with GnRH Agonist (GnRHa) on oocyte and embryo quality at the mitochondrial level: A retrospective and experimental study
Basar M, Olcay O, Akcay B, Aydin S, Neslihan M, Findikli N. P–273 Effects of ovulation induction with GnRH Agonist (GnRHa) on oocyte and embryo quality at the mitochondrial level: A retrospective and experimental study. Human Reproduction 2021, 36: deab130.272. DOI: 10.1093/humrep/deab130.272.Peer-Reviewed Original ResearchGnRHa-treated groupsGnRHa triggerHCG groupGnRHa groupEmbryo qualityGnRH agonistHsp60 levelsGnRHa injectionFemale BALB/c miceOvarian hyperstimulation syndrome riskOld female BALB/c miceWestern blotBALB/c miceTotal gonadotropin doseOocyte maturationOvarian hyperstimulation protocolTRIAL REGISTRATION NUMBERMid-cycle surgeInduction of ovulationPARTICIPANTS/MATERIALSNumber of oocytesBetter embryo qualityFinal oocyte maturationROLE OF CHANCEOocyte nuclear maturation
2009
Donor APCs Promote Gvhd in MHC-Mismatched Transplants by Indirectly Presenting Host Minor Histocompatibility Antigens.
Wang X, Martone C, Demetris A, McNiff J, Shlomchik W. Donor APCs Promote Gvhd in MHC-Mismatched Transplants by Indirectly Presenting Host Minor Histocompatibility Antigens. Blood 2009, 114: 689. DOI: 10.1182/blood.v114.22.689.689.Peer-Reviewed Original ResearchAntigen presenting cellsBALB/c miceHost minor histocompatibility antigensCD4 cellsMinor histocompatibility antigensT cellsC miceAcute GVHDAllogeneic MHCChronic GVHDDonor BMHistocompatibility antigensIndirect presentationFemale recipientsT cell receptor transgenic T cellsDay 7Bone marrow/stem cell transplantationFemale BALB/c miceHost antigen presenting cellsMale BALB/c miceRecipient antigen presenting cellsBALB/c modelAlloreactive CD4 cellsPrime T cellsStem cell transplantation
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