Trends in Receipt of Adjuvant Chemotherapy and its Impact on Survival in Resected Biliary Tract Cancers
Rhodin K, Liu A, Bartholomew A, Kramer R, Parameswaran A, Uronis H, Strickler J, Hsu D, Morse M, Shah K, Herbert G, Zani S, Nussbaum D, Allen P, Lidsky M. Trends in Receipt of Adjuvant Chemotherapy and its Impact on Survival in Resected Biliary Tract Cancers. Annals Of Surgical Oncology 2023, 30: 4813-4821. PMID: 37188803, PMCID: PMC10330866, DOI: 10.1245/s10434-023-13567-4.Peer-Reviewed Original ResearchConceptsBiliary tract cancerResected biliary tract cancerNational Cancer DatabaseAdjuvant chemotherapyGallbladder cancerIntrahepatic CCAExtrahepatic CCAMethodsThe National Cancer DatabaseMultivariate Cox proportional hazards methodBiliary tract cancer subtypesOdds of ACCox proportional hazards methodReceipt of adjuvant chemotherapyCurative-intent treatmentReceipt of ACFactors associated with receiptYear of diagnosisHigher comorbidity scoreProportional hazards methodStage of diseaseFactors associated with ACMultivariate logistic regressionAssociated with reduced oddsIII diseasePositive margins
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