The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek’s disease virus peptides by using an unprecedented binding motif
Halabi S, Ghosh M, Stevanović S, Rammensee H, Bertzbach L, Kaufer B, Moncrieffe M, Kaspers B, Härtle S, Kaufman J. The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek’s disease virus peptides by using an unprecedented binding motif. PLOS Biology 2021, 19: e3001057. PMID: 33901176, PMCID: PMC8101999, DOI: 10.1371/journal.pbio.3001057.Peer-Reviewed Original ResearchConceptsMarek's disease virusMarek's diseaseSusceptibility to Marek's diseaseSusceptibility to many viral diseasesViral diseasesAmino acidsHaplotype B2Disease virusMarekZoonotic pathogensFood speciesChickenOncogenic herpesvirusFood sourcesViral peptide epitopesComplex virusesMajor histocompatibility complexIn vitro infection systemPeptide motifsFoodClass II moleculesQuestions of mechanismExpress class II moleculesAntigenic peptides to T lymphocytesAcid
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