2025
Identification of a Coxiella burnetii outer membrane porin required for intracellular replication
Yang Z, Duncan-Lowey J, Roy C. Identification of a Coxiella burnetii outer membrane porin required for intracellular replication. Infection And Immunity 2025, 93: e00448-24. PMID: 40071978, PMCID: PMC11977307, DOI: 10.1128/iai.00448-24.Peer-Reviewed Original ResearchConceptsIntracellular replicationDot/Icm type IVB secretion systemType IVB secretion systemHost cellsIsogenic wild-type strainIntracellular replication defectsIVB secretion systemEpitope-tagged proteinsOuter membrane porinsTransposon mutagenesis screenWild-type strainEpitope-tagged versionHost cell functionsBacterial outer membraneSecretion systemMembrane porinsMutagenesis screenOuter membraneReplication defectsHuman Q feverBacterial porinsMutantsGram-negativeIntracellular pathogensPorin
2013
Six Innexins Contribute to Electrical Coupling of C. elegans Body-Wall Muscle
Liu P, Chen B, Altun Z, Gross M, Shan A, Schuman B, Hall D, Wang Z. Six Innexins Contribute to Electrical Coupling of C. elegans Body-Wall Muscle. PLOS ONE 2013, 8: e76877. PMID: 24130800, PMCID: PMC3793928, DOI: 10.1371/journal.pone.0076877.Peer-Reviewed Original ResearchConceptsUNC-9Body wall musclesC. elegans body wall muscleBody wall muscle cellsGap junctionsEpitope-tagged proteinsInnexinsTriple mutantPunctate localizationFunctions cellMutantsIntercellular junctionsDistinct populationsMuscle expressionGFPMuscle cellsJunctional currentsElectrical couplingFunctional propertiesCellsPromoterProteinSolid foundationExpressionPopulation
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