A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans
Houri-Ze'evi L, Korem Y, Sheftel H, Faigenbloom L, Toker I, Dagan Y, Awad L, Degani L, Alon U, Rechavi O. A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans. Cell 2016, 165: 88-99. PMID: 27015309, DOI: 10.1016/j.cell.2016.02.057.Peer-Reviewed Original ResearchConceptsAncestral responsesSmall RNAsC. elegansRNAi responseEndogenous small RNAsSilencing of genesRNA sequencing analysisRNA inheritanceHeritable silencingRNAi factorsExposure to dsRNAManipulating genesEpigenetic responsesComplementary sequencesEpigenetic effectsGenesRNAiTransgenerational effectsSilencingRNAFeedback loopInheritance mechanismDsRNAElegansAncestor
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