2012
Simvastatin Decreases Invasiveness of Human Endometrial Stromal Cells1
Sokalska A, Cress A, Bruner-Tran KL, Osteen KG, Taylor HS, Ortega I, Duleba AJ. Simvastatin Decreases Invasiveness of Human Endometrial Stromal Cells1. Biology Of Reproduction 2012, 87: 2, 1-6. PMID: 22492974, PMCID: PMC3406552, DOI: 10.1095/biolreprod.111.098806.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell AdhesionEndometriosisEndometriumFemaleGene ExpressionHumansHyaluronan ReceptorsHydroxymethylglutaryl-CoA Reductase InhibitorsMatrix Metalloproteinase 2Matrix Metalloproteinase 3MiceMice, NudePolyisoprenyl PhosphatesPrenylationSesquiterpenesSimvastatinStromal CellsTissue Inhibitor of Metalloproteinase-2ConceptsEffect of simvastatinMatrix metalloproteinase-2Metalloproteinase-2Human endometrial stromal cellsEndometrial stromal cellsNude mouse modelConcentration-dependent reductionInhibition of HMGCREffects of GGPPInhibition of geranylgeranylationEndometrial implantsEndometrial stromaSimvastatin treatmentMouse modelAnimal modelsTissue inhibitorTIMP2 mRNASimvastatinDecrease invasivenessDecrease proliferationStromal cellsPresence of GGppCell invasivenessMRNA levelsEndometriosis
2010
Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1
Bruner-Tran KL, Osteen KG, Taylor HS, Sokalska A, Haines K, Duleba AJ. Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1. Biology Of Reproduction 2010, 84: 106-112. PMID: 20844278, PMCID: PMC3012565, DOI: 10.1095/biolreprod.110.086744.Peer-Reviewed Original ResearchConceptsEffects of resveratrolEndometrial tissueEndometriotic implantsEndometrial implantsNude miceMatrigel invasionOophorectomized nude miceCell invasivenessAnti-inflammatory propertiesHuman endometrial tissueDevelopment of endometriosisCommon gynecologic disorderNude mouse modelConcentration-dependent reductionExperimental endometriosisGynecologic disordersIntraperitoneal injectionHealthy donorsTissue injectionMouse modelEndometriosisNovel treatmentsMiceInhibits developmentResveratrol
2003
The broad-spectrum chemokine inhibitor NR58-3.14.3 suppresses the implantation and progression of human endometrial implants in the nude mice endometriosis model
Berkkanoglu M, Zhang L, Kayisli U, Senturk L, Luk J, Arici A. The broad-spectrum chemokine inhibitor NR58-3.14.3 suppresses the implantation and progression of human endometrial implants in the nude mice endometriosis model. Fertility And Sterility 2003, 80: 31-32. DOI: 10.1016/s0015-0282(03)01884-3.Peer-Reviewed Original Research
1999
Interleukin-8 stimulates the adhesion of endometrial stromal cells to fibronectin
Garcia-Velasco J, Arici A. Interleukin-8 stimulates the adhesion of endometrial stromal cells to fibronectin. Fertility And Sterility 1999, 72: 336-340. PMID: 10439007, DOI: 10.1016/s0015-0282(99)00223-x.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsInterleukin-8IL-8 monoclonal antibodyStromal cellsMonoclonal antibodiesBenign gynecologic surgeryPathogenesis of endometriosisConcentration-dependent increaseConcentration-dependent mannerEndometrial implantsEndometrial diseaseGynecologic surgeryMAIN OUTCOMEAntibodiesStromal cell adhesionAdhesion assaysAcademic research laboratoriesCellsCell adhesionEndometriosisSurgeryPathogenesisDiseaseWomen
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