Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer
Ross S, Agin-Liebes G, Lo S, Zeifman R, Ghazal L, Benville J, Corso S, Real C, Guss J, Bossis A, Mennenga S. Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer. ACS Pharmacology & Translational Science 2021, 4: 553-562. PMID: 33860185, PMCID: PMC8033770, DOI: 10.1021/acsptsci.1c00020.Peer-Reviewed Original ResearchSuicidal ideationElevated levels of depressionPsilocybin-assisted psychotherapyLevels of depressionWithin-group reductionsAntisuicidal effectsPsilocybin treatmentAntidepressant medicationCancer diagnosisCompleted SuicideLoss of meaningBetween-group differencesApparent 2 weeksComposite scoreDemoralizationHeightened riskDepressionSuicideExploratory analysisMonths postdosingRandomized Controlled TrialsExistential distressIdeationHopelessnessHastened death
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