2024
Cardiovascular Risk Estimation and Stratification Among Individuals with Hypercholesterolemia
Bosco G, Mszar R, Piro S, Sabouret P, Gallo A. Cardiovascular Risk Estimation and Stratification Among Individuals with Hypercholesterolemia. Current Atherosclerosis Reports 2024, 26: 537-548. PMID: 38965183, DOI: 10.1007/s11883-024-01225-3.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresCardiovascular risk stratificationLow-density lipoprotein cholesterolCoronary artery calciumRisk stratificationRisk estimatesRisk scoreCardiovascular risk calculatorsEarly life stagesClinical risk scoreCardiovascular risk estimationNegative risk markersPersonalized treatment strategiesElevated lipid levelsImpact of hypercholesterolemiaCardiovascular risk predictionLife stagesArtery calciumInflammatory markersTreatment initiationLipid parameters
2021
Genetic determinants of LDL cholesterol and risk of intracerebral haemorrhage
Szejko N, Kirsch E, Falcone GJ. Genetic determinants of LDL cholesterol and risk of intracerebral haemorrhage. Current Opinion In Lipidology 2021, 32: 244-248. PMID: 34010223, PMCID: PMC10273781, DOI: 10.1097/mol.0000000000000761.Peer-Reviewed Original ResearchConceptsRisk of ICHIntracerebral hemorrhageLDL levelsLDL cholesterolInverse associationClinical trialsLipid levelsObservational studyCerebral small vessel diseaseWhite matter hyperintensity volumeLDL cholesterol levelsLow LDL levelsNontraumatic intracerebral hemorrhageSmall vessel diseaseElevated LDL levelsElevated lipid levelsVessel diseaseCholesterol levelsHigh burdenHyperintensity volumeHigh riskRole of lipidsHemorrhageStatinsRisk
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