Advancements in techniques for human iPSC-derived cardiomyocytes maturation: mechanical and electrical stimulation approaches
Lu Y, Liu Y, Yan Y, Fooladi S, Qyang Y. Advancements in techniques for human iPSC-derived cardiomyocytes maturation: mechanical and electrical stimulation approaches. Biophysical Reviews 2025, 17: 169-183. PMID: 40060015, PMCID: PMC11885779, DOI: 10.1007/s12551-024-01267-6.Peer-Reviewed Original ResearchHuman induced pluripotent stem cell-derived cardiomyocytesMaturity of human-induced pluripotent stem cell-derived cardiomyocytesPluripotent stem cell-derived cardiomyocytesStem cell-derived cardiomyocytesIon channel expressionCell-derived cardiomyocytesChannel expressionCo-culture systemElectrophysiological propertiesAdult cardiomyocytesCardiomyocyte maturationSynchronous contractionProtein expressionGrowth factorSarcomere alignmentClinical practiceElectrical pacingElectrical stimulation techniquesMaturation protocolsCardiomyocytesCo-CultureRegenerative medicineElectrical stimulation approachesDisease modelsDrug screening
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