2025
Impact of radiation therapy on the immunological tumor microenvironment
Guilbaud E, Naulin F, Meziani L, Deutsch E, Galluzzi L. Impact of radiation therapy on the immunological tumor microenvironment. Cell Chemical Biology 2025, 32: 678-693. PMID: 40280118, DOI: 10.1016/j.chembiol.2025.04.001.Peer-Reviewed Original ResearchConceptsImmunological tumor microenvironmentRadiation therapyTumor microenvironmentExternal beam radiation therapyImpact of radiation therapyBeam radiation therapyImpact tumor growthIrradiated cancer cellsEffects of RTModern cancer managementMalignant cellsPalliative settingImmune cellsTumor ecosystemTumor growthCancer managementTherapeutic windowClinical effectsCancer cellsNormal cellsCellular mechanismsHealthy tissueCytotoxic effectsTherapyDNA damage
2023
Analysis of Radiation Therapy Quality Assurance in NRG Oncology RTOG 0848
Tchelebi L, Winter K, Abrams R, Safran H, Regine W, McNulty S, Wu A, Du K, Seaward S, Bian S, Aljumaily R, Shivnani A, Knoble J, Crocenzi T, DiPetrillo T, Roof K, Crane C, Goodman K. Analysis of Radiation Therapy Quality Assurance in NRG Oncology RTOG 0848. International Journal Of Radiation Oncology • Biology • Physics 2023, 118: 107-114. PMID: 37598723, PMCID: PMC10843017, DOI: 10.1016/j.ijrobp.2023.08.014.Peer-Reviewed Original ResearchConceptsTarget volumeRadiation therapy quality assuranceRadiation therapyPlanning target volumeClinical treatment volumeGross target volumePretreatment QAContouring atlasTreatment planningResectable pancreatic head adenocarcinomaRT planningIntensity modulated RTQA analysisPancreatic head adenocarcinomaNRG Oncology RTOGPracticing radiation oncologistsReal-time quality assuranceTreatment volumeEffects of RTConcurrent fluoropyrimidineConformal RTAdjuvant chemotherapyRadiation oncologistsQuality assurancePancreas cancer
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