Norepinephrine but not Serotonin Reuptake Inhibitors Enhance Theta and Gamma Activity of the Septo-Hippocampal System
Hajós M, Hoffmann W, Robinson D, Yu J, Hajós-Korcsok É. Norepinephrine but not Serotonin Reuptake Inhibitors Enhance Theta and Gamma Activity of the Septo-Hippocampal System. Neuropsychopharmacology 2002, 28: 857-864. PMID: 12637957, DOI: 10.1038/sj.npp.1300116.Peer-Reviewed Original ResearchConceptsSerotonin reuptake inhibitor fluvoxamineReuptake inhibitorsSepto-hippocampal systemAntidepressant drugsSelective serotonin reuptake inhibitor fluvoxamineMedial septum/diagonal bandExtracellular single-unit recordingsOscillatory activitySelective NE reuptake inhibitorNorepinephrine reuptake inhibitorsEffective antidepressant drugsTheta frequencyExtracellular NE levelsHippocampal EEG recordingsNE reuptake inhibitorSingle-unit recordingsHippocampal oscillatory activityGamma wave activityNE levelsSystemic administrationAcute effectsDiagonal bandHuman depressionHippocampal formationHippocampal EEG
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