2010
CD4+ T cells mediate mucosal and systemic immune responses to experimental hookworm infection
DONDJI B, SUN T, BUNGIRO RD, VERMEIRE JJ, HARRISON LM, BIFULCO C, CAPPELLO M. CD4+ T cells mediate mucosal and systemic immune responses to experimental hookworm infection. Parasite Immunology 2010, 32: 406-413. PMID: 20500671, PMCID: PMC3241967, DOI: 10.1111/j.1365-3024.2010.01204.x.Peer-Reviewed Original ResearchConceptsT cellsImmune responseHookworm infectionHost cellular immune responseExperimental hookworm infectionT-cell depletionMesenteric lymph nodesSystemic immune responsesCellular immune responsesHumoral immune responseIntestinal nematode infectionsIntestinal worm burdenResource-limited countriesHookworm antigensLymph nodesSevere anemiaIntraperitoneal injectionLymphocyte proliferationHookworm Ancylostoma ceylanicumIsotype controlDisease pathogenesisWorm burdenSyrian hamstersAncylostoma ceylanicumEffector role
1990
Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion.
Gocinski B, Tigelaar R. Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. The Journal Of Immunology 1990, 144: 4121-8. PMID: 1971294, DOI: 10.4049/jimmunol.144.11.4121.Peer-Reviewed Original ResearchConceptsEffector cellsVivo depletionBALB/c miceEffector roleCS effector cellsMonoclonal antibody depletionMurine contact sensitivityDepletion of CD4Depletion of CD8Contact sensitivity responseRole of CD4Activity of CD8Delayed-type hypersensitivityT cell subsetsCutaneous hypersensitivity responseT-cell phenotypeImportant effector roleSubsequent flow cytometric analysisFlow cytometric analysisEnhanced earImmune lymphResidual CD4Adoptive transferSuppressor cellsDistinct CD4
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