Diagnosis and Treatment of Monogenic Hypertension in Children
Park J, Shin J. Diagnosis and Treatment of Monogenic Hypertension in Children. Yonsei Medical Journal 2023, 64: 77-86. PMID: 36719014, PMCID: PMC9892546, DOI: 10.3349/ymj.2022.0316.Peer-Reviewed Original ResearchConceptsMonogenic hypertensionBlood pressureGenetic architecture of BPResponse to antihypertensive medicationCharacteristics of early onsetGenetic architecturePositive family historyDecreased potassium levelsDysregulation of blood pressureIntravascular volume expansionCausative molecular pathwaysGenetic sequencesMortality in adulthoodLow reninRefractory hypertensionAldosterone levelsPolygenic hypertensionAntihypertensive agentsElectrolyte disordersImprove morbiditySodium reabsorptionAdrenal glandPediatric hypertensionFamily historyAntihypertensive medications
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