2024
12611 The Thyroid Adapts Remarkably to Overnutrition to Mitigate Hypothyroidism
Rampy J, Manzo A, Hoffsmith K, Loberg M, Wang H, Weiss V, Carrasco N. 12611 The Thyroid Adapts Remarkably to Overnutrition to Mitigate Hypothyroidism. Journal Of The Endocrine Society 2024, 8: bvae163.2092. PMCID: PMC11453901, DOI: 10.1210/jendso/bvae163.2092.Peer-Reviewed Original ResearchThyroid-stimulating hormoneThyroid-stimulating hormone stimulationPathogenesis of obesityThyroid hormonesTH levelsThyroid functionTH availabilityIncreased thyroid-stimulating hormoneMatching energy intakeDiet-induced weight gainSerum TH levelsWeight lossMale C57BL/6J miceER stress-related proteinsHigh-fat dietMild hypothyroidismThyroid impairmentStimulating hormoneFemale miceHypothyroid stateC57BL/6J miceAdrenomedullin 2Whole-body energy balanceVascular changesEnergy intake
2016
Adrenomedullin 2 activates extracellular-signal-regulated kinase in endothelial cells via a protein kinase C α-independent pathway
Guo X, Ju R, Cha C, Simons M. Adrenomedullin 2 activates extracellular-signal-regulated kinase in endothelial cells via a protein kinase C α-independent pathway. F1000Research 2016, 5: 26. DOI: 10.12688/f1000research.2420.1.Peer-Reviewed Original Research
2015
The novel tumor angiogenic factor, adrenomedullin-2, predicts survival in pancreatic adenocarcinoma
Hollander LL, Guo X, Salem RR, H. CH. The novel tumor angiogenic factor, adrenomedullin-2, predicts survival in pancreatic adenocarcinoma. Journal Of Surgical Research 2015, 197: 219-224. PMID: 25982376, DOI: 10.1016/j.jss.2014.11.002.Peer-Reviewed Original ResearchConceptsMitogen-activated protein kinase/extracellular signal-regulated kinaseProtein kinase/extracellular signal-regulated kinaseExtracellular signal-regulated kinaseSignal-regulated kinaseTotal cellular levelsAdrenomedullin 2Tumor angiogenesis factorVascular endothelial growth factor 2Microarray technologyGrowth factor 2Cellular levelNovel therapeutic targetPancreatic cancer tissuesProtein expressionFactor 2Angiogenesis factorsTherapeutic targetTumor angiogenic factorsTumor angiogenesisAngiogenic rolePotential roleWorse histologic gradePossible roleCancer tissuesPancreas cancer
2014
The Novel Tumor Angiogenic Factor, Adrenomedullin-2 (ADM2) Predicts Survival in Pancreatic Adenocarcinoma
Hollander L, Guo X, Salem R, Cha C. The Novel Tumor Angiogenic Factor, Adrenomedullin-2 (ADM2) Predicts Survival in Pancreatic Adenocarcinoma. Journal Of Surgical Research 2014, 186: 635-636. DOI: 10.1016/j.jss.2013.11.651.Peer-Reviewed Original ResearchAdrenomedullin 2Pancreatic adenocarcinoma
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