Inositol Polyphosphate-5-Phosphatase K (Inpp5k) Enhances Sprouting of Corticospinal Tract Axons after CNS Trauma
Kauer SD, Fink KL, Li EHF, Evans BP, Golan N, Cafferty W. Inositol Polyphosphate-5-Phosphatase K (Inpp5k) Enhances Sprouting of Corticospinal Tract Axons after CNS Trauma. Journal Of Neuroscience 2022, 42: 2190-2204. PMID: 35135857, PMCID: PMC8936595, DOI: 10.1523/jneurosci.0897-21.2022.Peer-Reviewed Original ResearchConceptsAdult corticospinal neuronsSpinal cord injuryCorticospinal neuronsCNS neuronsAxon growthCNS traumaCord injuryCorticospinal tractAdult CNS environmentChronic functional deficitsConcomitant functional recoveryCorticospinal tract neuronsNogo receptor 1Corticospinal tract axonsRetinal ganglion cellsRobust axon growthEmbryonic cortical neuronsEmbryonic CNS neuronsCortical strokeContusion injuryNeurologic recoveryTract neuronsSpinal contusionFunctional recoveryCST axons
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