2023
T65. GENES IN POSTMORTEM BRAIN TISSUE DIFFERENTIALLY EXPRESSED IN CHRONIC PAIN
Collier L, Seah C, Kozik E, Group T, Girgenti M, Huckins L, Johnston K. T65. GENES IN POSTMORTEM BRAIN TISSUE DIFFERENTIALLY EXPRESSED IN CHRONIC PAIN. European Neuropsychopharmacology 2023, 75: s196-s197. DOI: 10.1016/j.euroneuro.2023.08.350.Peer-Reviewed Original ResearchChronic painBackground Chronic painBone cancer painPain-related conditionsVEGF BFalse discovery rate correctionCancer painEndometrial cancerRheumatoid arthritisBrain gene expression datasetsGene expressionPainPsychiatric conditionsLinear regression modelsMultiple testingSpecific cell typesGene expression analysisCell typesRate correctionRegression modelsSurrogate variablesDifferential gene expression analysisDACCMeasured variablesExpression
2022
Experimental evidence for a child‐to‐adolescent switch in human amygdala‐prefrontal cortex communication: A cross‐sectional pilot study
Gee DG, Hanson C, Caglar LR, Fareri DS, Gabard‐Durnam L, Mills‐Finnerty C, Goff B, Caldera CJ, Lumian DS, Flannery J, Hanson SJ, Tottenham N. Experimental evidence for a child‐to‐adolescent switch in human amygdala‐prefrontal cortex communication: A cross‐sectional pilot study. Developmental Science 2022, 25: e13238. PMID: 35080089, PMCID: PMC9232876, DOI: 10.1111/desc.13238.Peer-Reviewed Original ResearchConceptsCross-sectional pilot studyAge-related switchAmygdala reactivityPresent cross-sectional pilot studyPilot studyAnterior cingulate cortex activationDorsal anterior cingulate cortex (dACC) activationAmygdala connectivityCortex activationPrefrontal cortexDACC activationAmygdalaPrefrontal functionChildhoodPrefrontal engagementEmotional behaviorChildhood experiencesAdolescenceVentromedial PFCDACCOpposite effectBayesian network analysisActivationVmPFCReverse information flow
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