2010
Lymphocytes Accelerate Epithelial Tight Junction Assembly: Role of AMP-Activated Protein Kinase (AMPK)
Tang XX, Chen H, Yu S, Zhang L, Caplan MJ, Chan HC. Lymphocytes Accelerate Epithelial Tight Junction Assembly: Role of AMP-Activated Protein Kinase (AMPK). PLOS ONE 2010, 5: e12343. PMID: 20808811, PMCID: PMC2925955, DOI: 10.1371/journal.pone.0012343.Peer-Reviewed Original ResearchConceptsTJ assemblyActivation of AMPKProtein kinaseEpithelial cellsCalcium switch experimentsEpithelial cell polaritySuppression of AMPKTight junction assemblyRole of AMPMadin-Darby canine kidney cellsCellular ATP levelsCanine kidney cellsTight junctionsCell polarityApicolateral borderJunction assemblyModel cell lineAMPK activationProper formationAdjacent epithelial cellsTJ formationChemical inhibitorsCalu-3 human airway epithelial cellsHuman airway epithelial cellsMDCK cells
2008
Chapter 4 Protein Trafficking in Polarized Cells
Duffield A, Caplan MJ, Muth TR. Chapter 4 Protein Trafficking in Polarized Cells. International Review Of Cytology 2008, 270: 145-179. PMID: 19081536, DOI: 10.1016/s1937-6448(08)01404-4.Peer-Reviewed Original ResearchConceptsEpithelial cellsProtein traffickingBasolateral membrane surfaceLipid traffickingPolarized cellsDynamic regulationSpecific lipidsAdjacent epithelial cellsCell typesBasolateral surfaceApical surfaceCertain cellsMembrane surfaceTraffickingProtein contentCellsSortingNumber of sortingsImmune systemRecent advancesMechanismProteinRegulationEpitheliumLipids
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