2022
Overview of the 2022 WHO Classification of Neuroendocrine Neoplasms
Rindi G, Mete O, Uccella S, Basturk O, La Rosa S, Brosens L, Ezzat S, de Herder W, Klimstra D, Papotti M, Asa S. Overview of the 2022 WHO Classification of Neuroendocrine Neoplasms. Endocrine Pathology 2022, 33: 115-154. PMID: 35294740, DOI: 10.1007/s12022-022-09708-2.Peer-Reviewed Original ResearchConceptsNeuroendocrine tumorsNeuroendocrine neoplasmsSomatostatin receptorsWHO classificationNon-neuroendocrineDifferential diagnosisWHO Classification of EndocrineExpression of somatostatin receptorsWHO classification of neuroendocrine neoplasmsG3 neuroendocrine tumorsAssociated with germline mutationsPancreatic neuroendocrine tumorsClassification of neuroendocrine neoplasmsEctopic hormone productionLoss of RbLoss of ATRXSite of originComposite tumorMetastatic lesionsAberrant p53Amphicrine tumorsEpithelial neoplasmsPrecursor lesionsTheranostic biomarkersGermline mutations
2005
Composite Glandular and Endocrine Tumors of the Stomach With Pancreatic Acinar Differentiation
Jain D, Eslami-Varzaneh F, Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite Glandular and Endocrine Tumors of the Stomach With Pancreatic Acinar Differentiation. The American Journal Of Surgical Pathology 2005, 29: 1524-1529. PMID: 16224221, DOI: 10.1097/01.pas.0000169498.89035.f9.Peer-Reviewed Original ResearchConceptsPancreatic acinar differentiationGlandular componentAbdominal painCytokeratin 20Endocrine tumorsCytokeratin 7Acinar differentiationEndocrine componentElevated serum lipase levelsPerigastric lymph nodesSerum lipase levelsExocrine pancreatic enzymesIntestinal goblet cellsColumnar epithelial cellsGastrointestinal hemorrhageLymph nodesAcute pancreatitisClinicopathologic findingsGastric foveolarLipase levelsPrimary tumorGastric neoplasmsComposite tumorImmunohistochemical stainsPancreatic polypeptide
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