A computable electronic health record ARDS classifier recapitulates an association between the MUC5B promoter polymorphism and ARDS in critically ill adults.
Kerchberger V, McNeil J, Zheng N, Chang D, Rosenberger C, Rogers A, Bastarache J, Feng Q, Wei W, Ware L. A computable electronic health record ARDS classifier recapitulates an association between the MUC5B promoter polymorphism and ARDS in critically ill adults. CHEST Critical Care 2025, 100150. DOI: 10.1016/j.chstcc.2025.100150.Peer-Reviewed Original ResearchElectronic health recordsCritically Ill AdultsElectronic health record dataMUC5B Promoter PolymorphismIll adultsAt-risk adultsNegative predictive valuePositive predictive valueDiagnostic billing codesHealth recordsHospital participationGenetic risk factorsDNA biobanksBilling codesBioVUStudy designPromoter polymorphismCohort of critically ill adultsAt-riskCohen's kappaModerate agreementRisk factorsGenotyped cohortPredictive valueBiobank
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