Soluble Collectin-12 (CL-12) Is a Pattern Recognition Molecule Initiating Complement Activation via the Alternative Pathway
Ma Y, Hein E, Munthe-Fog L, Skjoedt M, Bayarri-Olmos R, Romani L, Garred P. Soluble Collectin-12 (CL-12) Is a Pattern Recognition Molecule Initiating Complement Activation via the Alternative Pathway. The Journal Of Immunology 2015, 195: 3365-3373. PMID: 26290605, DOI: 10.4049/jimmunol.1500493.Peer-Reviewed Original ResearchConceptsSoluble pattern recognition moleculesPattern recognition moleculesUmbilical cord plasmaVascular endothelial cellsTerminal complement complexCollectin-12Natural soluble formWestern blot analysisCord plasmaAlternative pathwaySoluble formInnate immunityComplement activationSoluble collectinsWestern blotComplement complexEndothelial cellsC3b depositionCL-12Blot analysisHuman umbilical cord plasmaElectrophoretic mobility patternsCollectin familyA. fumigatusNovel mechanism
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