2009
Mesangial cell complement receptor 1‐related protein y limits complement‐dependent neutrophil accumulation in immune complex glomerulonephritis
Bao L, Wang Y, Chen P, Sarav M, Haas M, Minto A, Petkova M, Quigg R. Mesangial cell complement receptor 1‐related protein y limits complement‐dependent neutrophil accumulation in immune complex glomerulonephritis. Immunology 2009, 128: e895-e904. PMID: 19740350, PMCID: PMC2753953, DOI: 10.1111/j.1365-2567.2009.03102.x.Peer-Reviewed Original ResearchConceptsWild-type miceImmune complex glomerulonephritisCrry(-/-Complement receptor 1Weeks of immunizationNeutrophil infiltrationExpression of decay-accelerating factorMouse kidneyAlpha-smooth muscle actinLimits complement activationSerum C3 levelsImmune complex depositionProliferating Cell Nuclear AntigenPathogenesis of immune complex glomerulonephritisCell nuclear antigenMesangial cell proliferationDecay-accelerating factorAbsent stainingRenal expressionC3 levelsProliferative GNNeutrophil recruitmentGlomerular hypercellularityNeutrophil accumulationLevels several-fold
1998
K-ras Oncogene Mutations in Osteoclast-like Giant Cell Tumors of the Pancreas and Liver
Westra W, Sturm P, Drillenburg P, Choti M, Klimstra D, Albores-Saavedra J, Montag A, Offerhaus G, Hruban R. K-ras Oncogene Mutations in Osteoclast-like Giant Cell Tumors of the Pancreas and Liver. The American Journal Of Surgical Pathology 1998, 22: 1247-1254. PMID: 9777987, DOI: 10.1097/00000478-199810000-00010.Peer-Reviewed Original ResearchConceptsOsteoclast-like giant cell tumorOsteoclast-like giant cellsK-ras mutationsGiant cell tumorK-ras oncogeneK-rasGiant cellsCell tumorsEpithelial proliferationMononuclear cellsEpithelial markersAtypical intraductal epithelial proliferationEpithelial precursorsK-ras oncogene mutationsIntraductal epithelial proliferationMucinous cystic neoplasmsFinding of K-ras mutationsInfiltrating mononuclear cellsPhagocytize tumor cellsEnigmatic tumorsUndifferentiated carcinomaMesenchymal tumorsAbsent stainingEpithelial lesionsCystic neoplasms
1995
Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
Amemiya M, Loffing J, Lötscher M, Kaissling B, Alpern R, Moe O. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney International 1995, 48: 1206-1215. PMID: 8569082, DOI: 10.1038/ki.1995.404.Peer-Reviewed Original ResearchConceptsThick ascending limbAscending limbNHE-3H secretionNa/H exchanger isoformsProximal tubulesCortical thick ascending limbNa/H exchange activityS3 proximal tubuleDistal convoluted tubuleRat renal proximal tubulesNa/H exchangeH exchange activityRenal proximal tubulesRat NHE-3Apical membraneAbsent stainingMock-transfected cellsCortical membranesConvoluted tubulesInner stripeStrong stainingWeak stainingOuter medullaNa absorption
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