2011
The tammar wallaby major histocompatibility complex shows evidence of past genomic instability
Siddle H, Deakin J, Coggill P, Wilming L, Harrow J, Kaufman J, Beck S, Belov K. The tammar wallaby major histocompatibility complex shows evidence of past genomic instability. BMC Genomics 2011, 12: 421. PMID: 21854592, PMCID: PMC3179965, DOI: 10.1186/1471-2164-12-421.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsChromosomes, Artificial, BacterialEvolution, MolecularExpressed Sequence TagsGene DuplicationGenes, MHC Class IIGenomic InstabilityMacropodidaeMajor Histocompatibility ComplexMaleMolecular Sequence DataMultigene FamilyPhylogenyPhysical Chromosome MappingSequence AlignmentSequence Analysis, DNAConceptsGene organizationMajor histocompatibility complexGenomic instabilityEutherian mammalsBackgroundThe major histocompatibility complexRetroviral elementsAustralian marsupialsMajor histocompatibility complex regionMajor histocompatibility complex genesGroup of genesClass III genesUnique model organismEndogenous retroviral elementsClass II regionBAC clonesGene evolutionClass II genesChromosome 2qGene familyHistocompatibility complexIII genesModel organismsProcessing genesMHC regionNon-mammals
2009
Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts
Hussain A, Saraiva L, Korsching S. Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 4313-4318. PMID: 19237578, PMCID: PMC2657432, DOI: 10.1073/pnas.0803229106.Peer-Reviewed Original ResearchConceptsTrace amine-associated receptorsTAAR genesIntron gainGene familyClass IIIBony fishesOlfactory receptor neuronsPositive Darwinian selectionLocal positive selectionOlfactory receptor gene familyClass III genesOlfactory receptorsOlfactory receptor familyReceptor gene familyOlfactory epitheliumLigand-binding motifsFish genesTeleost lineageReceptor neuronsJawless vertebratesVertebrate evolutionIII genesPositive selectionDarwinian selectionEvolutionary dynamics
1989
The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro.
Gottlieb E, Steitz JA. The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro. The EMBO Journal 1989, 8: 841-850. PMID: 2498086, PMCID: PMC400883, DOI: 10.1002/j.1460-2075.1989.tb03445.x.Peer-Reviewed Original ResearchConceptsTranscription levelsNascent RNA polymerase III transcriptsRNA polymerase III transcriptionAbundant nuclear phosphoproteinRNA polymerase III transcriptsPolymerase III transcriptionPolymerase III transcriptsClass III genesHeLa cell extractsAction of LaTranscript lengthTermination signalNuclear phosphoproteinUridylate residuesLa proteinTranscription activityAutoantigen LaCell extractsTranscriptsRNAAbsence of LAMouse monoclonal antibodyTranscriptionPhosphoproteinGenes
1983
Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome
Wolin S, Steitz J. Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. Cell 1983, 32: 735-744. PMID: 6187471, DOI: 10.1016/0092-8674(83)90059-4.Peer-Reviewed Original ResearchConceptsHuman genomeRo RNAsSecondary structure homologyRNA polymerase IIISmall cytoplasmic ribonucleoproteinsClass III genesGenomic clonesMammalian cellsPolymerase IIIRNA componentStructure homologySingle copyCytoplasmic ribonucleoproteinHY5 RNAMouse cellsHuman cellsHY1Cell extractsGenesRNAGenomeRNAsHY3CellsMY1
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