2025
Developments in pharmacotherapy for the preservation of ovarian function during cancer treatment
Turan V, Oktay K. Developments in pharmacotherapy for the preservation of ovarian function during cancer treatment. Expert Opinion On Pharmacotherapy 2025, 26: 897-907. PMID: 40271805, DOI: 10.1080/14656566.2025.2495090.Peer-Reviewed Original ResearchConceptsOvarian functionPharmacological therapyPreservation of ovarian functionChemotherapy-induced ovarian damageCancer treatmentOvarian cortex cryopreservationProtect ovarian functionPremature ovarian failureHuman ovarian tissueDevelopment of pharmacological therapiesChemotherapy-induced damageFertility preservation proceduresTargeted pharmacological therapiesAnti-cancer therapyOvarian failureHuman ovaryOocyte apoptosisOvarian damageOvarian reservePreserving fertilityOvarian stromaChemotherapy typeChemotherapeutic agentsProtect ovariesOvarian tissue
2023
Chemotherapy-induced ovarian damage and protective strategies
Zhao P, Guo C, Du H, Xiao Y, Su J, Wang X, Yeung W, Li G, Wang T. Chemotherapy-induced ovarian damage and protective strategies. Human Fertility 2023, 26: 887-900. PMID: 38054300, DOI: 10.1080/14647273.2023.2275764.Peer-Reviewed Original ResearchP-613 Deletion of the CLPP gene in oocytes exacerbates chemotherapy-induced ovarian damage
Gu J, Guo C, Xiao Y, Hua R, Hai Z, Zhao P, Su J, Wang T. P-613 Deletion of the CLPP gene in oocytes exacerbates chemotherapy-induced ovarian damage. Human Reproduction 2023, 38 DOI: 10.1093/humrep/dead093.942.Peer-Reviewed Original ResearchChemotherapy-induced ovarian damageOvarian damageOocyte functionOocyte competenceChemotherapeutic drugsPremature ovarian insufficiencyChemotherapeutic drug cyclophosphamideOocyte-specific deletionTest of miceCaseinolytic peptidase PEarly embryo developmentClpP geneCyclophosphamide modelAneuploidy rateMII oocytesProportion of folliclesMII stageOvarian insufficiencyCKO miceWider implicationsChemotherapy drugsMouse modelMitochondrial distributionDrug cyclophosphamideOocyte maturation
2009
Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study Badawy A, Elnashar A, El-Ashry M, et al (Mansura Univ, Egypt; et al) Fertil Steril 91:694-697, 2009§
Oktay K, Sönmezer M. Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study Badawy A, Elnashar A, El-Ashry M, et al (Mansura Univ, Egypt; et al) Fertil Steril 91:694-697, 2009§. Breast Diseases A Year Book Quarterly 2009, 20: 458-460. DOI: 10.1016/s1043-321x(09)79420-2.Peer-Reviewed Original Research
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