2025
Acellular Tissue Engineered Vessels as Coronary Artery Bypass Grafts
Williams A, Nash K, Kirkton R, Levitan G, Daubert M, Whitney S, Naegeli K, Benkert A, McCartney S, Prichard H, Niklason L, Kypson A. Acellular Tissue Engineered Vessels as Coronary Artery Bypass Grafts. JACC Basic To Translational Science 2025, 10: 101379. PMID: 40939573, DOI: 10.1016/j.jacbts.2025.101379.Peer-Reviewed Original ResearchCoronary Artery Bypass GraftingRight coronary arteryComputed tomography angiographyArtery Bypass GraftingBypass GraftingCoronary arteryInternal mammary arterySmooth muscle cellsTissue engineered vesselTissue-engineered vesselsCoronary artery bypass grafting conduitsCardiac functionHost cell ingrowthMammary arteryMuscle cellsSaphenous veinPrimate modelCell ingrowthArteryAdult baboonsAngiographyGene expression patternsGraftExpression patterns
2016
Elastic, silk‐cardiac extracellular matrix hydrogels exhibit time‐dependent stiffening that modulates cardiac fibroblast response
Stoppel W, Gao A, Greaney A, Partlow B, Bretherton R, Kaplan D, Black L. Elastic, silk‐cardiac extracellular matrix hydrogels exhibit time‐dependent stiffening that modulates cardiac fibroblast response. Journal Of Biomedical Materials Research Part A 2016, 104: 3058-3072. PMID: 27480328, PMCID: PMC5805141, DOI: 10.1002/jbm.a.35850.Peer-Reviewed Original ResearchConceptsExtracellular matrix hydrogelTissue-derived extracellular matrixEndothelial cell ingrowthSilk hydrogelsMechanical propertiesCell ingrowthWeeks in vivoHydrogel stiffeningMatrix hydrogelHydrogelsFunctional cardiac repairStiffeningFocal adhesion proteinsCardiac fibroblastsExpression of integrinsCardiac repairHeart failureProgression to heart failureTissue in vitroAdhesion proteinsCell growthExtracellular matrix
2013
Agar-based bridges as biocompatible candidates to provide guide cues in spinal cord injury repair
Martín-López E, Darder M, Ruiz-Hitzky E, Sampedro M. Agar-based bridges as biocompatible candidates to provide guide cues in spinal cord injury repair. Bio-Medical Materials And Engineering 2013, 23: 405-421. PMID: 23988711, DOI: 10.3233/bme-130763.Peer-Reviewed Original ResearchConceptsEnvironmental scanning electron microscopyScanning electron microscopyPorous structureBridge materialsBiomaterial propertiesCell ingrowthChannel linearityMixture of agarGrowth surfaceXanthan gumStability of gelsElectron microscopyEmpty channelsBiopolymer structuresPolysulfoneMatrix scaffoldsBiocompatible candidateΚ-carrageenanClosed contactBridgeMaterialsGel mixtureMixtureSpinal cord injury repairStability
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