2025
A Digital Therapeutic Intervention for Inpatients With Elevated Suicide Risk
Bryan C, Simon P, Wilkinson S, Allen M, Perez J, Adler C, Moon K, Astorino L, Carpenter K, Misquitta L, Brownlowe K, Khazem L, Hay J, Starkey A, Tartaglia J, Winston H, Simpson S, Dager A, Feuerstein S. A Digital Therapeutic Intervention for Inpatients With Elevated Suicide Risk. JAMA Network Open 2025, 8: e2525809. PMID: 40779267, PMCID: PMC12334960, DOI: 10.1001/jamanetworkopen.2025.25809.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyActual suicide attemptsElevated suicide riskSuicidal ideationSuicide attemptsSuicide riskFollow-up suicide attemptsTrajectories of suicidal ideationRate of suicide attemptsRecurrent suicide attemptsSuicide risk assessmentSuicide attempt ratePsychiatric inpatient unitBehavioral therapySuicidal behaviorTherapeutic interventionsSupportive listeningIdeationTherapeutic groupsClinical improvementRandomized clinical trialsOutpatient treatmentAttempt rateSuicideSuicide prevention
2022
Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium
van Velzen LS, Dauvermann MR, Colic L, Villa LM, Savage HS, Toenders YJ, Zhu AH, Bright JK, Campos AI, Salminen LE, Ambrogi S, Ayesa-Arriola R, Banaj N, Başgöze Z, Bauer J, Blair K, Blair RJ, Brosch K, Cheng Y, Colle R, Connolly CG, Corruble E, Couvy-Duchesne B, Crespo-Facorro B, Cullen KR, Dannlowski U, Davey CG, Dohm K, Fullerton JM, Gonul AS, Gotlib IH, Grotegerd D, Hahn T, Harrison BJ, He M, Hickie IB, Ho TC, Iorfino F, Jansen A, Jollant F, Kircher T, Klimes-Dougan B, Klug M, Leehr EJ, Lippard ETC, McLaughlin KA, Meinert S, Miller AB, Mitchell PB, Mwangi B, Nenadić I, Ojha A, Overs BJ, Pfarr JK, Piras F, Ringwald KG, Roberts G, Romer G, Sanches M, Sheridan MA, Soares JC, Spalletta G, Stein F, Teresi GI, Tordesillas-Gutiérrez D, Uyar-Demir A, van der Wee NJA, van der Werff SJ, Vermeiren RRJM, Winter A, Wu MJ, Yang TT, Thompson PM, Rentería ME, Jahanshad N, Blumberg HP, van Harmelen AL, Schmaal L. Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium. Molecular Psychiatry 2022, 27: 4550-4560. PMID: 36071108, PMCID: PMC9734039, DOI: 10.1038/s41380-022-01734-0.Peer-Reviewed Original ResearchConceptsMood disordersSuicidal thoughtsSuicide attemptsBrain alterationsMRI metricsSuicidal ideationColumbia-Suicide Severity Rating ScaleStructural brain alterationsLifetime suicide attemptsSeverity Rating ScaleCurrent suicidal ideationActual suicide attemptsHealthy controlsAssessment instrumentsClinical controlEarly interventionMental disordersSignificant associationFrontal poleBrain morphologySuicide riskSuicide attemptersRating ScaleYoung peopleDisorders
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