2025
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth
Cheng A, Lichenstein S, Chaarani B, Liang Q, Babaeianjelodar M, Riley S, Luo W, Horien C, Greene A, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Martinot M, Artiges E, Nees F, Papadopoulos Orfanos D, Poustka L, Hohmann S, Holz N, Baeuchl C, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Constable R, Pearlson G, Garavan H, Yip S. Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth. Molecular Psychiatry 2025, 1-10. PMID: 40913110, DOI: 10.1038/s41380-025-03196-6.Peer-Reviewed Original ResearchFunctional connectivity signaturesNeural signaturesConnectivity signaturesConnectome-based predictive modelingUnique neural mechanismsFunctional connectivity dataStudy of adolescent developmentDimensional traitsNegative affectDimensional phenotypesDefault modeNeural mechanismsNeuroticismAlcohol-useCerebellar networkYouth impulsivityAdolescent developmentCanonical networksAssociated with riskConnectivity dataNetwork anatomyComplex neural networksImpulseRisk behaviorsTraits
2023
Developmental differences in functional organization of multispectral networks
Petro N, Picci G, Embury C, Ott L, Penhale S, Rempe M, Johnson H, Willett M, Wang Y, Stephen J, Calhoun V, Doucet G, Wilson T. Developmental differences in functional organization of multispectral networks. Cerebral Cortex 2023, 33: 9175-9185. PMID: 37279931, PMCID: PMC10505424, DOI: 10.1093/cercor/bhad193.Peer-Reviewed Original ResearchConceptsSpontaneous cortical activityPhase coherenceImaginary partFunctional magnetic resonance imaging measuresConsistent with previous workFunctional brain organizationLimbic cortical regionsFunctional organizationBrain connectivityFunction of increasing ageEyes-closed restGamma bandSpectral specificityConnectivity matrixBrain regionsCanonical deltaBrain organizationBrain activityFunctional connectivityDevelopmental differencesBandCortical regionsCanonical networksCortical activityMagnetic resonance imaging measures
2019
Connectome-Based Prediction of Cocaine Abstinence
Yip SW, Scheinost D, Potenza MN, Carroll KM. Connectome-Based Prediction of Cocaine Abstinence. American Journal Of Psychiatry 2019, 176: 156-164. PMID: 30606049, PMCID: PMC6481181, DOI: 10.1176/appi.ajp.2018.17101147.Peer-Reviewed Original ResearchMeSH KeywordsAdultBehavior TherapyBrainCholinesterase InhibitorsCocaine-Related DisordersCognitionConnectomeExecutive FunctionFemaleFunctional NeuroimagingGalantamineHumansIndividualityMachine LearningMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysOpiate Substitution TreatmentOpioid-Related DisordersPrognosisRewardTreatment OutcomeConceptsConnectome-based predictive modelingCocaine use disorderUse disordersBrain-based predictorsLarge-scale neural networksFunctional MRI dataCocaine abstinenceExecutive controlReward responsivenessIndividual differencesBaseline cocaine usePosttreatment assessmentConnectivity strengthHeterogeneous sampleAbstinenceIndependent samplesNovel interventionsCanonical networksSpecific behaviorsCocaine useSignificant correspondenceDisordersTreatment outcomesNetwork strengthMRI data
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