2002
Brain Incorporation of [11C]Arachidonic Acid in Young Healthy Humans Measured With Positron Emission Tomography
Giovacchini G, Chang M, Channing M, Toczek M, Mason A, Bokde A, Connolly C, Vuong B, Ma Y, Der M, Doudet D, Herscovitch P, Eckelman W, Rapoport S, Carson R. Brain Incorporation of [11C]Arachidonic Acid in Young Healthy Humans Measured With Positron Emission Tomography. Cerebrovascular And Brain Metabolism Reviews 2002, 22: 1453-1462. DOI: 10.1097/00004647-200212000-00006.Peer-Reviewed Original ResearchPositron emission tomographyArachidonic acidBrain incorporationEmission tomographyHuman brainCerebral blood volumeYoung healthy humansYoung healthy adultsRole of AAVivo quantitative methodBrain radioactivityAwake ratsHealthy humansPharmacological activationBlood volumeRat studiesHealthy adultsWhite matterArterial input functionBrainPhospholipase A2Important second messengerSignal transductionTomographySecond messenger
2000
Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans.
Varrone A, Fujita M, Verhoeff NP, Zoghbi SS, Baldwin RM, Rajeevan N, Charney DS, Seibyl JP, Innis RB. Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans. Journal Of Nuclear Medicine 2000, 41: 1343-51. PMID: 10945525.Peer-Reviewed Original ResearchConceptsTest-retest variabilityTemporal cortexTest-retest reproducibilityOutcome measuresExtrastriatal regionsD2 receptorsPlasma clearanceExtrastriatal dopamine D2 receptorsGood test-retest variabilityConstant infusion paradigmExtrastriatal D2 receptorsDopamine D2 receptorsBrain radioactivityStriatal radioactivityHealthy volunteersReceptor densityInfusion rateParent tracerSPECT studiesLess test-retest variabilityCortexHigh test-retest variabilityFree fractionReceptor quantificationReceptors
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