2005
Mutational analysis of the ARAF gene in human cancers
LEE J, SOUNG Y, KIM S, PARK W, NAM S, MIN W, KIM S, LEE J, YOO N, LEE S. Mutational analysis of the ARAF gene in human cancers. Apmis 2005, 113: 54-7. PMID: 15676015, DOI: 10.1111/j.1600-0463.2005.apm1130108.x.Peer-Reviewed Original ResearchConceptsRaf family membersHuman cancersKinase domainDownstream pathways of RasMOLT-4 leukemia cell lineDownstream pathwaysGene mutationsDetection of somatic mutationsRas signal transductionGrowth of human cancer cellsAmino acid substitutionsCell linesHuman cancer cellsPathogenesis of human cancersBRAF geneLeukemia cell linesHuman cancer tissuesCancer cell linesGenomic DNAAcid substitutionsCancer tissuesSignal transductionHuman cancer cell linesRas pathwayMutation analysis
2003
Mutational analysis of Noxa gene in human cancers
LEE S, SOUNG Y, LEE J, KIM H, LEE J, KIM H, LEE J, PARK J, CHO Y, KIM C, KIM S, PARK W, KIM S, LEE J, YOO N. Mutational analysis of Noxa gene in human cancers. Apmis 2003, 111: 599-604. PMID: 12969015, DOI: 10.1034/j.1600-0463.2003.1110602.x.Peer-Reviewed Original ResearchConceptsSingle strand conformation polymorphismNoxa geneSomatic mutationsBcl-2 homology 3 (BH3)-only memberHuman cancersAnti-apoptotic Bcl-2 family membersBcl-2Bcl-2 family membersMutation analysisBcl-2 familyDetection of somatic mutationsStrand conformation polymorphismDysregulation of apoptosisApoptosis-related genesCell death mechanismsPolymerase chain reactionPathogenesis of human cancersTransitional cell carcinomaMechanisms of cancer developmentSplice siteDNA sequencesCoding regionConformation polymorphismNoxaDeath mechanisms
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