2022
Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
Jiang J, Taylor DK, Kim EJ, Boyd LF, Ahmad J, Mage MG, Truong HV, Woodward CH, Sgourakis NG, Cresswell P, Margulies DH, Natarajan K. Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nature Communications 2022, 13: 5470. PMID: 36115831, PMCID: PMC9482634, DOI: 10.1038/s41467-022-33153-8.Peer-Reviewed Original Research
1993
Elevated serum levels of neopterin but not β2-microglobulin in HIV-1-seronegative injecting drug users
Strickler H, Blanchard J, Vlahov D, Taylor E, Muñoz A, Nelson K, Margolick J. Elevated serum levels of neopterin but not β2-microglobulin in HIV-1-seronegative injecting drug users. AIDS 1993, 7: 361-368. PMID: 8471199, DOI: 10.1097/00002030-199303000-00009.Peer-Reviewed Original ResearchConceptsDrug useNeopterin levelsSerum levelsDrug usersSerum beta 2MBeta 2M levelsSerum beta 2M levelsMean neopterin levelsSerum neopterin levelsElevated serum levelsHIV-1 infectionCellular immune activationBeta 2MRisk factor variablesIntravenous Experience (ALIVE) studyM levelsMale IDUsSerum neopterinImmune activationProspective studyImmunocompetent cellsHIV-1Β2-microglobulinConsecutive daysNeopterin
1987
An epitope common to HLA class I and class II antigens, Ig light chains, and β2-microglobulin
Lutz P, Cresswell P. An epitope common to HLA class I and class II antigens, Ig light chains, and β2-microglobulin. Immunogenetics 1987, 25: 228-233. PMID: 2437022, DOI: 10.1007/bf00404692.Peer-Reviewed Original ResearchConceptsB-lymphoblastoid cell linesClass I heavy chainsWestern blottingClass I major histocompatibility complex antigensClass II MHC antigensMajor histocompatibility complex antigensClass IHLA class I heavy chainsClass II antigensHistocompatibility complex antigensHLA class IBeta-2-microglobulinLight chainHeavy chainNormal human serumWestern blot analysisMHC antigensII antigensComplex antigensImmunoglobulin light chainsM1 mAbΒ2-microglobulinMonoclonal antibodiesAntigenHuman immunoglobulin
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