2020
Dstac Regulates Excitation-Contraction Coupling in Drosophila Body Wall Muscles
Hsu IU, Linsley JW, Reid LE, Hume RI, Leflein A, Kuwada JY. Dstac Regulates Excitation-Contraction Coupling in Drosophila Body Wall Muscles. Frontiers In Physiology 2020, 11: 573723. PMID: 33123029, PMCID: PMC7573238, DOI: 10.3389/fphys.2020.573723.Peer-Reviewed Original ResearchExcitation-contraction couplingL-type voltage-gated calcium channelsVoltage-gated calcium channelsSubset of neuronsBody wall musclesL-type CaCalcium channelsNormal expression levelsEC couplingMuscle contractionSkeletal muscleSpecific antibodiesMuscleLarval body wall musclesDmca1DExpression levelsWall musclesNormal locomotionDrosophila body wall musclesNeuronsVertebrate skeletal muscleAntibodiesDeficient larvae
2016
Regression of metastatic, radiation/chemotherapy-resistant uterine serous carcinoma overexpressing HER2/neu with trastuzumab emtansine (TDM-1)
Santin AD, Bellone S, Buza N, Schwartz PE. Regression of metastatic, radiation/chemotherapy-resistant uterine serous carcinoma overexpressing HER2/neu with trastuzumab emtansine (TDM-1). Gynecologic Oncology Reports 2016, 19: 10-12. PMID: 28018954, PMCID: PMC5175991, DOI: 10.1016/j.gore.2016.12.003.Peer-Reviewed Original ResearchTDM-1Remarkable clinical responsesAlternative therapeutic optionUterine serous carcinomaNovel treatment optionsAbdominal wall musclesUSC patientsClinical responseTumor depositsSerous carcinomaTherapeutic optionsTreatment optionsTrastuzumab emtansineComplete resolutionCAT scanSystemic controlWall musclesPatientsCarcinomaHER2NeuChemotherapyEmtansineSurgeryOptions
2015
An Evolutionarily Conserved Switch in Response to GABA Affects Development and Behavior of the Locomotor Circuit of Caenorhabditis elegans
Han B, Bellemer A, Koelle MR. An Evolutionarily Conserved Switch in Response to GABA Affects Development and Behavior of the Locomotor Circuit of Caenorhabditis elegans. Genetics 2015, 199: 1159-1172. PMID: 25644702, PMCID: PMC4391577, DOI: 10.1534/genetics.114.173963.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidRigorous genetic analysisBody wall musclesNeural circuit developmentCaenorhabditis elegansL1 animalsDevelopmental switchGenetic analysisGABAergic neuronsGABA responsesVertebrate brainMammalian neuronsStage animalsNeurotransmitter gamma-aminobutyric acidWall musclesChloride transportersMajor inhibitory neurotransmitterMuscle targetsTransporter 1Muscimol responsesGABA neuronsLocomotor circuitsExcitatory responsesCircuit developmentAgonist muscimol
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply