2017
Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts
Albrecht D, Normandin M, Shcherbinin S, Wooten D, Schwarz A, Zürcher N, Barth V, Guehl N, Akeju O, Atassi N, Veronese M, Turkheimer F, Hooker J, Loggia M. Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts. Journal Of Nuclear Medicine 2017, 59: 107-114. PMID: 28818984, PMCID: PMC5750517, DOI: 10.2967/jnumed.116.178335.Peer-Reviewed Original ResearchConceptsChronic low back painPseudoreference regionGroup differencesDistribution volume ratioOccipital cortexArterial input functionChronic low back pain patientsAbsence of group differencesNo significant group differencesTranslocator protein imagingLow back painRegional group differencesSignificant group differencesAmyotrophic lateral sclerosisTranslocator proteinMatched healthy controlsDetect group differencesWithin-group variabilityBack painNeuroimmune activationVoxelwise analysisPET scansHealthy controlsClinical cohortDistribution volume
2016
Reduced Frontoparietal Activity in Schizophrenia Is Linked to a Specific Deficit in Goal Maintenance: A Multisite Functional Imaging Study
Poppe AB, Barch DM, Carter CS, Gold JM, Ragland JD, Silverstein SM, MacDonald AW. Reduced Frontoparietal Activity in Schizophrenia Is Linked to a Specific Deficit in Goal Maintenance: A Multisite Functional Imaging Study. Schizophrenia Bulletin 2016, 42: 1149-1157. PMID: 27060129, PMCID: PMC4988742, DOI: 10.1093/schbul/sbw036.Peer-Reviewed Original ResearchConceptsHealthy controlsGroup differencesImaging studiesWhole-brain voxelwise analysisPosterior parietal lobeFunctional imaging studiesMiddle frontal gyrus activityAttention network dysfunctionMinutes of scanningSpecific deficitsSignificant group differencesSpecific performance deficitsNetwork dysfunctionFunctional magnetic resonance imaging (fMRI) scannerParietal lobeSchizophreniaVoxelwise analysisDisorganization symptomsMagnetic resonance imaging (MRI) scannerPatientsReduced activityScan lengthDeficitsExecutive functionPerformance deficits
2011
Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging
Urban NB, Slifstein M, Meda S, Xu X, Ayoub R, Medina O, Pearlson GD, Krystal JH, Abi-Dargham A. Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging. Psychopharmacology 2011, 221: 67-77. PMID: 22052081, DOI: 10.1007/s00213-011-2543-6.Peer-Reviewed Original ResearchConceptsPositron emission tomography studyMonetary incentive delay taskDopamine releaseVentral striatumBOLD activationVoxelwise analysisFMRI BOLD activationEndogenous dopamine releaseEmission tomography studiesROI analysisMesolimbic dopamine releaseFunctional magnetic resonance imagingMagnetic resonance imagingPositron emission tomographyReward processingBOLD signal changesFunctional neuroimaging studiesPrecommissural putamenIncentive delay taskSignal changesPosterior caudateStriatal subregionsHealthy subjectsGlutamatergic signalingPercent change
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply