2016
The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Shook B, Rivera Gonzalez G, Ebmeier S, Grisotti G, Zwick R, Horsley V. The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches. Annual Review Of Cell And Developmental Biology 2016, 32: 1-23. PMID: 27146311, PMCID: PMC5157158, DOI: 10.1146/annurev-cellbio-111315-125426.Peer-Reviewed Original ResearchConceptsStem cell nicheFunction of WATWhite adipose tissueTissue homeostasisCell nicheMetabolic regulationNovel roleMetabolic physiologyMajor regulatorMature adipocytesImmune tissuesVivo regulationEssential roleRole of adipocytesHomeostasisWhite adipocytesAdipocytesTissue regenerationRegulationEndocrine homeostasisRegenerationTissueNicheRegulatorRole
2010
In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development
Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J. In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development. The Journal Of Immunology 2010, 185: 313-326. PMID: 20519643, PMCID: PMC2891136, DOI: 10.4049/jimmunol.0904023.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CommunicationCell DifferentiationCricetinaeDNA-Binding ProteinsDown-RegulationFemaleImmunophenotypingLymphocyte CooperationMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMice, TransgenicProto-Oncogene Proteins c-bcl-6SpleenT-Lymphocyte SubsetsT-Lymphocytes, Helper-InducerUp-RegulationConceptsPD-1 upregulationIL-21IL-6B cellsFollicular helper T cellsFollicular helper cell developmentDeath receptor-1Helper T cellsCytokines IL-6B cell interactionsB cell maturationTranscriptional repressor BCL6Vivo regulationCell developmentP-selectin glycoprotein ligand-1New surface markersT cellsGerminal centersInitial upregulationReceptor 1CXCR5BCL6 upregulationCell maturationSurface markersBCL6 expression
1995
In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis.
Shulman R, Bloch G, Rothman D. In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 8535-8542. PMID: 7567971, PMCID: PMC41002, DOI: 10.1073/pnas.92.19.8535.Peer-Reviewed Original ResearchConceptsCovalent phosphorylationGlycogen synthesisGlycogen synthaseMuscle glycogen synthaseVivo NMR methodsPositive allosteric effectorMetabolic control theoryAllosteric effectorsVivo regulationGSaseVivo NMR experimentsNMR experimentsPhosphorylationSynthesis fluxProximal stepMuscle glycogen synthesisSynthaseVivo NMRRegulationNMR methodsMetabolite levelsHuman muscleRat muscleEffectorsEnzyme
1987
Physiological Role of Cholecystokinin in Meal-Induced Insulin Secretion in Conscious Rats: Studies With L 364718, A Specific Inhibitor of CCK-Receptor Binding
Rossetti L, Shulman G, Zawalich W. Physiological Role of Cholecystokinin in Meal-Induced Insulin Secretion in Conscious Rats: Studies With L 364718, A Specific Inhibitor of CCK-Receptor Binding. Diabetes 1987, 36: 1212-1215. PMID: 3308589, DOI: 10.2337/diab.36.10.1212.Peer-Reviewed Original ResearchConceptsPlasma insulinPostprandial plasma insulinGut hormone cholecystokininImportant physiologic roleCCK receptor bindingIntraduodenal catheterInsulin outputPrior administrationConscious ratsEnteroinsular axisGlucagon concentrationsVehicle injectionCCK antagonistsCCK secretionProtein ingestionInsulin secretionSpecific antagonistHormone cholecystokininCholecystokininPhysiologic roleInsulinAntagonistGlucagonRatsVivo regulation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply