Lessons from KEEPS: the Kronos Early Estrogen Prevention Study
Miller VM, Taylor HS, Naftolin F, Manson JE, Gleason CE, Brinton EA, Kling JM, Cedars MI, Dowling NM, Kantarci K, Harman SM. Lessons from KEEPS: the Kronos Early Estrogen Prevention Study. Climacteric 2020, 24: 139-145. PMID: 32880220, PMCID: PMC8108428, DOI: 10.1080/13697137.2020.1804545.Peer-Reviewed Original ResearchConceptsKronos Early Estrogen Prevention StudyCarotid intima-medial thicknessPrevention StudyCardiovascular diseaseOral conjugated equine estrogenClinical CVD eventsUse of MHTOvert cardiovascular diseasePlacebo-controlled trialConjugated equine estrogensCoronary artery calciumIntima-medial thicknessMode of deliveryUptake of estrogensMood/anxietyAge-related increaseGenetic variantsCVD eventsAgatston unitsArtery calciumSymptom reliefPlacebo pillsEquine estrogensMenopausal womenMenopausal symptoms
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