2006
Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis
Guarín N, Palma G, Pirmez C, Valderrama L, Tovar R, Saravia NG. Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis. Biomédica 2006, 26: 38-48. PMID: 17361840, DOI: 10.7705/biomedica.v26i1.1498.Peer-Reviewed Original ResearchConceptsSkin test reactionsMontenegro skin testSkin testChronic lesionsAcute lesionsAsymptomatic infectionT lymphocytesImmune responseB cellsComparative immunohistological analysisProportion of CD4Chronic cutaneous leishmaniasisType hypersensitivity reactionCellular immune responsesSkin test sitesTest reactionsLeishmaniasis lesionsCellular infiltrateHypersensitivity reactionsLeishmania infectionChronic diseasesInflammatory responseChronic patientsT cellsCutaneous leishmaniasis
2005
HPV16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities
Santin AD, Bellone S, Palmieri M, Ravaggi A, Romani C, Tassi R, Roman JJ, Burnett A, Pecorelli S, Cannon MJ. HPV16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities. Gynecologic Oncology 2005, 100: 469-478. PMID: 16249018, DOI: 10.1016/j.ygyno.2005.09.040.Peer-Reviewed Original ResearchConceptsCervical cancer patientsStandard treatment modalityAutologous dendritic cellsT cell responsesDendritic cellsCancer patientsTreatment modalitiesHPV16/18 E7Clinical responseIFN-gammaAutologous monocyte-derived dendritic cellsE7 oncoproteinsLate-stage cervical cancer patientsCell responsesMonocyte-derived dendritic cellsHuman recombinant interleukin-2Active vaccination strategiesHPV18 E7 oncoproteinLimited tumor burdenTreatment-induced immunosuppressionAutologous tumor cellsDendritic cell vaccinationObjective clinical responsesEarly-stage diseaseType hypersensitivity reaction
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