2024
Radiation Therapy for the Treatment of Osteoarthritis
Yu J, Grew D, Spraker M, Beckta J, Shah C, Brower J. Radiation Therapy for the Treatment of Osteoarthritis. Practical Radiation Oncology 2024, 15: 19-24. PMID: 39503700, DOI: 10.1016/j.prro.2024.09.003.Peer-Reviewed Original ResearchConceptsRadiation therapyAssessment of treatment responseTreatment of osteoarthritisMedically refractory diseaseNonsteroidal anti-inflammatory drugsNoninvasive treatment optionCause of painCyclooxygenase-2 inhibitorsIntra-articular corticosteroid therapyAnti-inflammatory drugsCorticosteroid therapyRefractory diseaseTreatment responseTreatment optionsClinical evidenceOlder patientsTherapyCyclooxygenase-2PatientsTraditional treatmentPhysical therapyPainTreatmentOsteoarthritisTechnical considerations
2018
Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis
Hurley E, Yasui Y, Gianakos A, Seow D, Shimozono Y, Kerkhoffs G, Kennedy J. Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy 2018, 26: 3499-3507. PMID: 29713784, DOI: 10.1007/s00167-018-4955-x.Peer-Reviewed Original ResearchConceptsStromal vascular fractionPlatelet-rich plasmaTreatment of osteoarthritisClinical outcomesSystematic reviewForm of SVFUse of SVFAdipose-derived stem cell therapyEffects of ADSCsIncidence of swellingFavorable clinical outcomeLevel IV studiesCochrane Library databasesEffects of AdiposeDonor siteStem cell therapySVF injectionComplication rateBiological adjuvantsClinical studiesLevel IVExclusion criteriaLibrary databasesSide effectsAdipose tissue
2008
COX-2 Selective Inhibitors in the Treatment of Osteoarthritis
Laine L, White WB, Rostom A, Hochberg M. COX-2 Selective Inhibitors in the Treatment of Osteoarthritis. Seminars In Arthritis And Rheumatism 2008, 38: 165-187. PMID: 18177922, DOI: 10.1016/j.semarthrit.2007.10.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTraditional nonsteroidal antiinflammatory drugsNonsteroidal antiinflammatory drugsTreatment of osteoarthritisBlood pressureNonselective nonsteroidal antiinflammatory drugsCyclooxygenase-2 selective inhibitorCOX-2 selective inhibitorsClinical liver injuryHepatic side effectsSignificant renal dysfunctionCongestive heart failureSelective inhibitorAminotransferase elevationClinical hepatotoxicityGastrointestinal complicationsHypertensive patientsRenal dysfunctionUlcer complicationsCardiovascular riskSevere painGastroduodenal ulcersHeart failureLiver injuryOA patientsRandomized trials
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply