2023
Sleep deficiency among people living with human immunodeficiency virus: A growing challenge
Reisert H, Miner B, Farhadian S. Sleep deficiency among people living with human immunodeficiency virus: A growing challenge. HIV Medicine 2023, 25: 5-15. PMID: 37485570, PMCID: PMC10803648, DOI: 10.1111/hiv.13526.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusSleep qualitySleep deficiencyImmunodeficiency virusSleep durationHIV-specific factorsSelf-reported sleep qualitySleep timingAntiretroviral therapy drugsObjective sleep qualityAntiretroviral therapyEpidemiological correlatesHigh-quality researchSociodemographic factorsClinical implicationsNarrative reviewTherapy drugsMental healthMore high-quality researchPLWHLongitudinal studyDeficiencyObjective measuresDurationVirus
2019
A systematic analysis of off-label drug use in real-world data (RWD) across more than 145,000 cancer patients.
McCafferty J, Grover K, Li L, Li Z, Fink M, Goldsweig H, Ma M, Zhou X, Mullaney T, Redfern A, Jappe W, Zimmerman M, Prentice T, Pan Q, Oh W, Schadt E, Li D, Chen R. A systematic analysis of off-label drug use in real-world data (RWD) across more than 145,000 cancer patients. Journal Of Clinical Oncology 2019, 37: e18031-e18031. DOI: 10.1200/jco.2019.37.15_suppl.e18031.Peer-Reviewed Original ResearchRefractory multiple myelomaHormonal therapy drugsLabel drug useTreatment discontinuationCheckpoint inhibitorsDrug useClinical responseCancer patientsLabel useClinical trialsClinical studiesChemotherapy drugsOff-label drug useTherapy drugsImmune checkpoint inhibitorsThorough chart reviewFuture clinical studiesMount Sinai HospitalAdverse eventsChart reviewMM patientsImmunotherapy drugsHormonal agentsMultiple myelomaTesticular cancer
2017
Astrocyte Senescence and Metabolic Changes in Response to HIV Antiretroviral Therapy Drugs
Cohen J, D’Agostino L, Wilson J, Tuzer F, Torres C. Astrocyte Senescence and Metabolic Changes in Response to HIV Antiretroviral Therapy Drugs. Frontiers In Aging Neuroscience 2017, 9: 281. PMID: 28900395, PMCID: PMC5581874, DOI: 10.3389/fnagi.2017.00281.Peer-Reviewed Original ResearchHIV-Associated Neurocognitive DisordersHAART drugsHuman astrocytesDevelopment of HIV-associated neurocognitive disordersTreatment induced cell cycle arrestHIV-infected patientsMetabolic changesNeurocognitive disordersAntiretroviral therapy treatmentPrimary cultures of human astrocytesAntiretroviral therapy drugsCultures of human astrocytesCell cycle inhibitor p21Senescence-associated beta-galactosidaseInduction of reactive oxygen speciesAntiretroviral therapyMarkers of senescenceCell cycle arrestAstrocyte senescenceHAARTTherapy drugsPrimary culturesSurvival rateIncreased glycolysisNeurocognitive impairment
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