Increased Brain Transport and Metabolism of Acetate in Hypoglycemia Unawareness
Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS. Increased Brain Transport and Metabolism of Acetate in Hypoglycemia Unawareness. The Journal Of Clinical Endocrinology & Metabolism 2013, 98: 3811-3820. PMID: 23796565, PMCID: PMC4425818, DOI: 10.1210/jc.2013-1701.Peer-Reviewed Original ResearchConceptsHypoglycemia-associated autonomic failureHypoglycemia unawarenessT1DM individualsEpinephrine levelsBrain transportControl groupType 1 diabetes mellitusDefective glucose counterregulationHealthy nondiabetic controlsSevere hypoglycemia unawarenessIntensive insulin therapyLong-term complicationsHospital research unitEntire study populationT1DM participantsAutonomic failureGlucose counterregulationInsulin therapyDiabetes mellitusNondiabetic controlsCerebral cortexAcute hypoglycemiaT1DM controlsCerebral energeticsStudy population
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply