2015
Untwisting the Caenorhabditis elegans embryo
Christensen RP, Bokinsky A, Santella A, Wu Y, Marquina-Solis J, Guo M, Kovacevic I, Kumar A, Winter PW, Tashakkori N, McCreedy E, Liu H, McAuliffe M, Mohler W, Colón-Ramos D, Bao Z, Shroff H. Untwisting the Caenorhabditis elegans embryo. ELife 2015, 4: e10070. PMID: 26633880, PMCID: PMC4764590, DOI: 10.7554/elife.10070.Peer-Reviewed Original ResearchConceptsCaenorhabditis elegansLate embryogenesisSeam cell nucleiSingle cell developmentNematode Caenorhabditis elegansEmbryonic nervous systemSystems-level viewWorm embryoInaccessible periodDevelopmental eventsCell developmentEmbryogenesisCell nucleiPositional informationElegansEmbryosLive embryosNeurodevelopmental eventsEmbryo movementAnnotation softwareCellsNervous systemEnough neuronsDetailed positional informationNeurons
2011
An expression map for Anopheles gambiae
MacCallum R, Redmond S, Christophides G. An expression map for Anopheles gambiae. BMC Genomics 2011, 12: 620. PMID: 22185628, PMCID: PMC3341590, DOI: 10.1186/1471-2164-12-620.Peer-Reviewed Original ResearchConceptsPeptidoglycan recognition proteinsGene familyAnopheles gambiaeGene expressionA. gambiaeIndividual gene clustersMosquito Anopheles gambiaeDistinct biological contextsImmunity-related genesHouse-keeping roleSystems-level viewEvolutionary historyMolecular functionsGene clusterMost organismsTranscriptome dataIndividual genesDistinct functional groupsDNA replicationRecognition proteinsExpression mapProtein degradationPathogen recognitionBiological contextProtein products
2007
A Functional and Regulatory Map of Asthma
Novershtern N, Itzhaki Z, Manor O, Friedman N, Kaminski N. A Functional and Regulatory Map of Asthma. American Journal Of Respiratory Cell And Molecular Biology 2007, 38: 324-336. PMID: 17921359, PMCID: PMC2258452, DOI: 10.1165/rcmb.2007-0151oc.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAllergensAnimalsAsthmaDisease Models, AnimalGene Expression ProfilingHumansHypersensitivityImmunity, InnateInterleukin-13MiceMice, Inbred AMice, Inbred BALB CMice, Inbred C3HMice, KnockoutModels, BiologicalOligonucleotide Array Sequence AnalysisOvalbuminProtein Interaction MappingReproducibility of ResultsSystems BiologyTranscription, GeneticTransforming Growth Factor beta1ConceptsCo-regulated gene modulesGene expression compendiumProtein interaction networksModule network analysisMouse microarray datasetsSystems-level viewExpression compendiumRegulatory mapGene modulesModule membersFunctional themesInteraction networksKey regulatorAnimal modelsMicroarray datasetsGeneral inductionAnnotation setsChronic inflammatory airway diseasesMorbidity of asthmaInflammatory airway diseasesMechanisms of asthmaAdaptive immune responsesSystem-level approachSimilar roleDistinct responses
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