2025
Stem cells and female reproduction: endometrial physiology, disease and therapy
Cevik E, Mamillapalli R, Taylor H. Stem cells and female reproduction: endometrial physiology, disease and therapy. Stem Cells 2025, 43: sxaf016. PMID: 40317260, DOI: 10.1093/stmcls/sxaf016.Peer-Reviewed Original ResearchConceptsBone marrow-derived mesenchymal stem cellsStem cellsKnowledge of stem cell biologyStem cell-based therapiesEngraftment of stem cellsRecurrent pregnancy lossImprove pregnancy outcomesEndometrial progenitor cellsMinimally invasive techniquesProgenitor stem cellsCell-based therapiesStem cell biologyAsherman's syndromeCells to areasPotential therapeutic avenuePregnancy outcomesThin endometriumHuman endometriumMarrow-derived mesenchymal stem cellsTargeted therapyEndometrial repairEndometrial regenerationPregnancy lossImplant failureInvasive techniques
2021
Adipose-Derived Stem Cells Therapy for Radiation-Induced Skin Injury
Huayllani MT, Ruiz-Garcia H, Boczar D, Avila FR, Lu X, Rinker BD, Moran SL, Sarabia-Estrada R, Quiñones-Hinojosa A, Forte AJ. Adipose-Derived Stem Cells Therapy for Radiation-Induced Skin Injury. Annals Of Plastic Surgery 2021, 87: 639-649. PMID: 34724441, DOI: 10.1097/sap.0000000000003039.Peer-Reviewed Original ResearchConceptsRadiation-induced skin injuryAdipose-derived stem cell therapySkin injuryStem cell therapyCell therapyDifferent medical therapiesWound healingAdipose-derived stem cell-based therapyNon-English studiesUse of ADSCsMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsStem cell-based therapiesMedical therapyCell-based therapiesEmbase databasesOvid MEDLINEInclusion criteriaAdipose-derived stem cellsReporting ItemsSystematic reviewTherapyInjuryExperimental modelMeSH terms
2019
Are all stem cells equal? Systematic review, evidence map, and meta-analyses of preclinical stem cell-based therapies for bronchopulmonary dysplasia
Augustine S, Cheng W, Avey MT, Chan ML, Lingappa SMC, Hutton B, Thébaud B. Are all stem cells equal? Systematic review, evidence map, and meta-analyses of preclinical stem cell-based therapies for bronchopulmonary dysplasia. Stem Cells Translational Medicine 2019, 9: 158-168. PMID: 31746123, PMCID: PMC6988768, DOI: 10.1002/sctm.19-0193.Peer-Reviewed Original ResearchConceptsMesenchymal stromal cellsCell-based therapiesBronchopulmonary dysplasiaStem cell-based therapiesSystematic reviewDifferent cell-based therapiesExperimental neonatal lung injuryAvailable preclinical dataNeonatal lung injuryPreterm birth complicationsClinical translationPreclinical experimental designLung injuryUnclear riskBirth complicationsPreclinical dataEffective therapyPreclinical studiesRodent modelsSuccessful clinical translationHead comparisonTherapyStromal cellsSelect outcomesCell productsCritical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiation
Xiang Q, Yang B, Li L, Qiu B, Qiu C, Gao X, Zhou H, Min W. Critical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiation. Journal Of Cellular And Molecular Medicine 2019, 23: 0-0. PMID: 30734494, PMCID: PMC6433861, DOI: 10.1111/jcmm.14202.Peer-Reviewed Original ResearchConceptsCardiac stem cell activationStem cell activationHuman inducible pluripotent stem cellsCardiac stem cell differentiationCSC activationStem cell differentiationInducible pluripotent stem cellsPluripotent stem cellsCardiac progenitor cellsCritical roleActivation of TNFR2Factor RNACell activationProtein Lin28Cardiomyocyte proteinsCell differentiationStem cellsProgenitor cellsStem cell-based therapiesCSC differentiationProtein expressionDifferentiationCell-based therapiesExpressionActivation
2017
Systemic administration of bone marrow‐derived cells leads to better uterine engraftment than use of uterine‐derived cells or local injection
Liu Y, Tal R, Pluchino N, Mamillapalli R, Taylor HS. Systemic administration of bone marrow‐derived cells leads to better uterine engraftment than use of uterine‐derived cells or local injection. Journal Of Cellular And Molecular Medicine 2017, 22: 67-76. PMID: 28782281, PMCID: PMC5742714, DOI: 10.1111/jcmm.13294.Peer-Reviewed Original ResearchConceptsBM-derived cellsSystemic administrationFluorescence-activated cell sortingLocal injectionBone marrow-derived cellsSingle uterine hornMarrow-derived cellsWild-type recipientsStem cell engraftmentStem cell-based therapiesAsherman's syndromeCell-based therapiesIntrauterine injectionUterine injuryEndometrial cellsSystemic injectionLocal injuryImmunohistochemical stainingUterine tissuePotential therapyCell recruitmentSystemic routeAdministration resultsUterine hornCell engraftment
2010
Implantation failure: molecular mechanisms and clinical treatment
Cakmak H, Taylor HS. Implantation failure: molecular mechanisms and clinical treatment. Human Reproduction Update 2010, 17: 242-253. PMID: 20729534, PMCID: PMC3039220, DOI: 10.1093/humupd/dmq037.Peer-Reviewed Original ResearchConceptsGynecological diseasesEndometrial receptivityImplantation rateImplantation failureOptimal current therapyPolycystic ovarian syndromeStem cell-based therapiesSynchronized dialogueOvarian syndromePregnancy outcomesCell-based therapiesImplantation markersSuccessful pregnancySurgical interventionCurrent therapiesEndometrial cellsUterine receptivityAbnormal cytokineAnimal modelsEndometrial genesClinical treatmentEmbryo qualityFertility treatmentExact mechanismDisease
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