2018
Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications
Young B, Oatmen K, Freeburg L, Zellars K, Sapp A, Herzog E, Miller E, Spinale F. Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications. Journal Of Cardiac Failure 2018, 24: s10. DOI: 10.1016/j.cardfail.2018.07.033.Peer-Reviewed Original ResearchCardiac sarcoidosisCardiac inflammationSarcoid patientsReceptor levelsEpidermal growth factorNormal subjectsSoluble tumor necrosis factor receptor IITumor necrosis factor receptor IIFluorodeoxyglucose positron emission tomographyPro-inflammatory signaling pathwaysAnti-inflammatory regimensMethods Plasma samplesHeart failure therapySoluble receptor levelsSpecific inflammatory pathwaysSpecific therapeutic targetingInflammatory signaling cascadesSpecific therapeutic targetsPositron emission tomographyCytokine receptor profilesCardiac involvementFailure therapyPrognostic valueTreatment regimensInflammatory pathways
2014
Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model
Kunjithapatham R, Karthikeyan S, Geschwind JF, Kieserman E, Lin M, Fu DX, Ganapathy-Kanniappan S. Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model. Scientific Reports 2014, 4: 6816. PMID: 25351825, PMCID: PMC4212233, DOI: 10.1038/srep06816.Peer-Reviewed Original ResearchConceptsMetastatic phenotypeAnchorage-independent growthMolecular regulationMulticellular spheroidsStem cell markersMolecular eventsCancer stem cell markersVitro modelModel of metastasisMetastatic processSpecific therapeutic targetsTherapeutic targetAntimetastatic agentPhenotypeMetastatic modelRegulationVivo dataExpressionChemoresistanceInvasivenessSpheroidsMajor impedimentInductionMimicsGrowth
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