2025
Outcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial
Malas M, Hamouda M, Farber A, Menard M, Conte M, Rosenfield K, Strong M, Doros G, Powell R, Mena-Hurtado C, Gasper W, Schermerhorn M, Allievi S, Smolderen K, Dake M, Rymer J, Tuttle K. Outcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial. Journal Of Vascular Surgery 2025, 81: 945-956.e3. PMID: 39846933, DOI: 10.1016/j.jvs.2024.12.128.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalChronic Limb-Threatening IschemiaEndovascular ProceduresFemaleGlomerular Filtration RateHumansIschemiaKidneyLimb SalvageMaleMiddle AgedPeripheral Arterial DiseaseProspective StudiesRenal DialysisRenal Insufficiency, ChronicRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic limb-threatening ischemiaChronic kidney diseaseDialysis-dependent patientsBEST-CLIChronic kidney disease stagePrimary trial outcomeRisk of amputationAssociated with lower mortalityEndovascular therapyAll-Cause MortalityHigh risk of poor outcomesRisk of poor outcomesEndovascular revascularizationKidney diseaseBEST-CLI trialOutcomes of lower extremity revascularizationAssociated with better survivalMultivariate Cox regression analysisBest Surgical TherapyIncreased reintervention rateStage 4 CKD patientsRisk of reinterventionGroup C patientsAdverse limb eventsChronic kidney disease severity
2024
The impact of diabetes mellitus on the outcomes of revascularization for chronic limb-threatening ischemia in the BEST-CLI trial
Ochoa Chaar C, Malas M, Doros G, Schermerhorn M, Conte M, Alameddine D, Siracuse J, Yadavalli S, Dake M, Creager M, Tan T, Rosenfield K, Menard M, Farber A, Hamdan A. The impact of diabetes mellitus on the outcomes of revascularization for chronic limb-threatening ischemia in the BEST-CLI trial. Journal Of Vascular Surgery 2024, 81: 376-385.e3. PMID: 39332785, DOI: 10.1016/j.jvs.2024.09.026.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaAnkle amputationLower extremity revascularizationBEST-CLI trialBEST-CLILimb-threatening ischemiaAll-cause deathDiabetes mellitusChronic obstructive pulmonary diseaseImpact of diabetes mellitusImpact of DMObstructive pulmonary diseasePotential confoundersBest Surgical TherapyAnkleAdverse limb eventsToe pressureBest EndovascularAnkle pressureRenal diseaseAmputationObservational studyOptimal medical therapyOutcomes of patientsCompared to patients
2023
Perioperative complications following open or endovascular revascularization for chronic limb-threatening ischemia in the BEST-CLI Trial
Siracuse J, Farber A, Menard M, Conte M, Kaufman J, Jaff M, Kiang S, Ochoa Chaar C, Osborne N, Singh N, Tan T, Guzman R, Strong M, Hamza T, Doros G, Rosenfield K. Perioperative complications following open or endovascular revascularization for chronic limb-threatening ischemia in the BEST-CLI Trial. Journal Of Vascular Surgery 2023, 78: 1012-1020.e2. PMID: 37318428, DOI: 10.1016/j.jvs.2023.05.040.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaSingle-segment great saphenous veinLimb-threatening ischemiaRisk-adjusted analysisCohort 2Cohort 1BEST-CLICardiovascular eventsEndovascular revascularizationPerioperative complicationsRevascularization strategyLower extremity bypass surgeryMajor adverse cardiovascular eventsBest Surgical TherapyBEST-CLI trialPeri-procedure complicationsAdverse cardiovascular eventsPeri-procedural complicationsThirty-day mortalityAcute renal failureGreat saphenous veinEndovascular revascularization strategiesBest EndovascularPerioperative morbidityBypass surgery
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply