2017
Reprimo tissue-specific expression pattern is conserved between zebrafish and human
Figueroa RJ, Carrasco-Avino G, Wichmann IA, Lange M, Owen GI, Siekmann AF, Corvalán AH, Opazo JC, Amigo JD. Reprimo tissue-specific expression pattern is conserved between zebrafish and human. PLOS ONE 2017, 12: e0178274. PMID: 28562620, PMCID: PMC5451059, DOI: 10.1371/journal.pone.0178274.Peer-Reviewed Original ResearchConceptsTissue-specific expression patternsExpression patternsGene familyExpression profilesSpatiotemporal expression profilesSitu hybridizationP53-mediated cell cycle arrestG2/M.Tumor suppressor geneUnique expression profileCell cycle arrestZebrafish developmentPhylogenetic analysisMost speciesMalignant tumor progressionGene transcriptsZebrafishProtein productsSpatiotemporal expressionCycle arrestReprimoCentral nervous systemPathological roleModel systemRT-qPCRChapter 15 Comparative Functions of miRNAs in Embryonic Neurogenesis and Neuronal Network Formation
Ristori E, Nicoli S. Chapter 15 Comparative Functions of miRNAs in Embryonic Neurogenesis and Neuronal Network Formation. 2017, 265-282. DOI: 10.1016/b978-0-12-804402-5.00015-7.Peer-Reviewed Original ResearchTarget mRNA degradationCell fate determinationGene regulatory pathwaysDynamic spatiotemporal expressionImportance of miRNAsSmall noncoding RNAsStem cell proliferationMulticellular organismsFate determinationMost miRNAsNeuronal network formationTranslational repressionModel organismsNeural stem cell proliferationMRNA degradationPosttranscriptional regulatorsNoncoding RNAsRegulatory pathwaysDevelopmental processesEmbryonic neurogenesisGene expressionSpatiotemporal expressionNovel roleNeuronal differentiationMiRNAs
2014
Laminar and Temporal Expression Dynamics of Coding and Noncoding RNAs in the Mouse Neocortex
Fertuzinhos S, Li M, Kawasawa YI, Ivic V, Franjic D, Singh D, Crair M, Šestan N. Laminar and Temporal Expression Dynamics of Coding and Noncoding RNAs in the Mouse Neocortex. Cell Reports 2014, 6: 938-950. PMID: 24561256, PMCID: PMC3999901, DOI: 10.1016/j.celrep.2014.01.036.Peer-Reviewed Original ResearchConceptsTemporal expression dynamicsExpression dynamicsDistinct biological processesGene coexpression networksSpecific spatiotemporal expressionSmall RNAsNoncoding RNAsTranscriptional differencesTranscriptional eventsSplicing patternsCoexpression networkMRNA interactionsPotential miRNATranscriptional overlapDeep sequencingBiological processesSpatiotemporal expressionMouse neocortexCell typesTranscriptsStudies of neurodevelopmentIntegrated viewTemporal dynamicsCharacteristic setTranscriptome
2011
Mouse Conjunctival Forniceal Gene Expression during Postnatal Development and Its Regulation by Krüppel-like Factor 4
Gupta D, Harvey SA, Kaminski N, Swamynathan SK. Mouse Conjunctival Forniceal Gene Expression during Postnatal Development and Its Regulation by Krüppel-like Factor 4. Investigative Ophthalmology & Visual Science 2011, 52: 4951-4962. PMID: 21398290, PMCID: PMC3176043, DOI: 10.1167/iovs.10-7068.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsConjunctivaEpithelial CellsFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalGenotypeGoblet CellsIn Situ HybridizationKruppel-Like Factor 4Kruppel-Like Transcription FactorsMaleMiceOligonucleotide Array Sequence AnalysisReverse Transcriptase Polymerase Chain ReactionTranscription FactorsConceptsKLF4 target genesGene expressionTarget genesEts transcription factor family memberCell developmentTranscription factor family membersGene regulatory networksGoblet cell developmentLaser microdissectionComponents of pathwaysTranscription factor SPDEFFactor family membersMesenchymal-epithelial transitionKrüppel-like factor 4Regulatory networksRegulatory targetsRole of KLF4Spatiotemporal expressionQuantitative RT-PCRGlycoprotein biosynthesisMucosal epitheliumGoblet cellsGenesKLF4Transcripts
2002
Expression of PKD1 and PKD2 Transcripts and Proteins in Human Embryo and during Normal Kidney Development
Chauvet V, Qian F, Boute N, Cai Y, Phakdeekitacharoen B, Onuchic LF, Attié-Bitach T, Guicharnaud L, Devuyst O, Germino GG, Gubler MC. Expression of PKD1 and PKD2 Transcripts and Proteins in Human Embryo and during Normal Kidney Development. American Journal Of Pathology 2002, 160: 973-983. PMID: 11891195, PMCID: PMC1867156, DOI: 10.1016/s0002-9440(10)64919-x.Peer-Reviewed Original ResearchConceptsPolycystin-1Kidney developmentPolycystin-2Expression patternsPKD1 expressionHuman genetic disordersLarge transmembrane proteinCell-matrix interactionsNormal kidney developmentMutations of PKD1Expression of PKD1Northern blot analysisGenes decreasesTransmembrane proteinHuman embryogenesisEndodermal derivativesSpatiotemporal expressionUreteric budPKD1 transcriptPKD2Transmembrane glycoproteinTranscriptsPKD1Nephron developmentProtein
1997
In situ expression of PLP/DM‐20, MBP, and CNP during embryonic and postnatal development of the jimpy mutant and of transgenic mice overexpressing PLP
Peyron F, Timsit S, Thomas J, Kagawa T, Ikenaka K, Zalc B. In situ expression of PLP/DM‐20, MBP, and CNP during embryonic and postnatal development of the jimpy mutant and of transgenic mice overexpressing PLP. Journal Of Neuroscience Research 1997, 50: 190-201. PMID: 9373029, DOI: 10.1002/(sici)1097-4547(19971015)50:2<190::aid-jnr8>3.0.co;2-a.Peer-Reviewed Original ResearchConceptsPLP/DMCyclic nucleotide phosphodiesteraseDM-20PLP geneMyelin basic proteinDM-20 mRNAPattern of expressionEmbryonic developmentLevel of expressionJimpy mutantPeripheral nervous systemTransgenic micePrecursors of oligodendrocytesSpatiotemporal expressionDistinct poolsNeural tubeCentral nervous system
1996
Orphan nuclear receptor RORα gene: isoform-specific spatiotemporal expression during postnatal development of brain
Sashihara S, Felts P, Waxman S, Matsui T. Orphan nuclear receptor RORα gene: isoform-specific spatiotemporal expression during postnatal development of brain. Brain Research 1996, 42: 109-117. PMID: 8915586, DOI: 10.1016/s0169-328x(96)00118-0.Peer-Reviewed Original ResearchConceptsROR alphaAlpha cDNAOrphan nuclear receptor ROR alphaSpatiotemporal expressionN-terminal regionIsoform-specific regulationAlpha expressionSpecific transcriptsCell typesHybridization signalsPurkinje cellsCDNAExpressionPostnatal developmentRelative levelsRegulationCellsAlphaPostnatal maturationTranscriptsOlfactory bulbRodent brainIsoformsBrain regionsMaturation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply