2011
Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post‐transcriptional regulation in the spontaneously hypertensive rat model of ADHD
Wigestrand MB, Mineur YS, Heath CJ, Fonnum F, Picciotto MR, Walaas SI. Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post‐transcriptional regulation in the spontaneously hypertensive rat model of ADHD. Journal Of Neurochemistry 2011, 119: 240-250. PMID: 21824140, PMCID: PMC3171636, DOI: 10.1111/j.1471-4159.2011.07415.x.Peer-Reviewed Original ResearchMeSH KeywordsAconitineAnimalsAttention Deficit Disorder with HyperactivityAzetidinesBrain ChemistryBridged Bicyclo Compounds, HeterocyclicBungarotoxinsIn Vitro TechniquesKineticsMaleMembranesNicotinic AgonistsNicotinic AntagonistsProtein Processing, Post-TranslationalPyridinesRatsRats, Inbred SHRRats, Inbred WKYReceptors, NicotinicReverse Transcriptase Polymerase Chain ReactionRNA, MessengerThermodynamicsConceptsAttention-deficit/hyperactivity disorderQuantitative real-time PCRBrain regionsCerebellum of SHRWistar-Kyoto rat controlsHypertensive rat modelMRNA levelsNicotinic receptor numbersCentral nicotinic receptorsSpecific brain regionsAdditional brain regionsSHR brainHypertensive ratsRat modelReal-time PCRNicotinic receptorsReceptor numberEpidemiological studiesLevels of mRNAΑ4β2 nAChRsSHRWKYNAChRsHyperactivity disorderStrain differences
1995
Na+/H+ antiporter (NHE-1 isoform) in cultured vascular smooth muscle from the spontaneously hypertensive rat
LaPointe M, Ye M, Moe O, Alpern R, Batlle D. Na+/H+ antiporter (NHE-1 isoform) in cultured vascular smooth muscle from the spontaneously hypertensive rat. Kidney International 1995, 47: 78-87. PMID: 7731174, DOI: 10.1038/ki.1995.9.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cellsCultured aortic vascular smooth muscle cellsWistar/Kyoto ratsAortic vascular smooth muscle cellsWKY ratsHypertensive ratsNominal absenceCultured vascular smooth muscleVascular smooth muscleSmooth muscle cellsCell acidificationRate of intracellularNormotensive controlsKyoto ratsNHE-1 isoformWKY cellsSmooth muscleSHRHigh functional activityRatsMuscle cellsThymidine incorporationPresence of HCO3Exchange activityHCO3-/CO2
1990
Stz-Induced Diabetes in Shr and Renovascular Hypertensive Rats: Dissociation Between Changes in Arterial Pressure and Vascular Collagen Synthesis
Mariani M, Sessa W, Chichester C, Rodgers R. Stz-Induced Diabetes in Shr and Renovascular Hypertensive Rats: Dissociation Between Changes in Arterial Pressure and Vascular Collagen Synthesis. Clinical And Experimental Hypertension 1990, 12: 1003-1019. PMID: 2245511, DOI: 10.3109/10641969009073514.Peer-Reviewed Original ResearchConceptsRenovascular hypertensive ratsVascular collagen synthesisArterial pressureHypertensive ratsCollagen synthesisSTZ induced diabetesLeft renal arteryNormotensive WKY ratsSTZ-induced diabetesWistar-Kyoto ratsNondiabetic SHRRVH ratsRenovascular hypertensionWKY controlsNormotensive controlsRenal arteryWKY ratsProlyl hydroxylase activitySHRDiabetesRatsHydroxylase activityProline incorporationHypertensionWKY
1989
Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats
Sessa W, Abraham N, Escalante B, Schwartzman M. Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats. Journal Of Hypertension 1989, 7: 37-42. PMID: 2708811, DOI: 10.1097/00004872-198901000-00006.Peer-Reviewed Original ResearchConceptsHeme oxygenase activityThromboxane synthase activityHypertensive ratsRenal heme oxygenase activitySeven-week-old SHRRenal cortical microsomesSystolic blood pressureMicrosomal heme oxygenase activityRenal cytochrome PCytochrome PSynthase activityThromboxane A2 formationCortical microsomesBlood pressureOxygenase activityBody weightA2 formationHemoprotein synthesisConsecutive daysControl levelsThromboxane synthaseSHRRatsHeme contentHeme availability
1986
Emotional hyperthermia in spontaneously hypertensive rats
Hajós M, Engberg G. Emotional hyperthermia in spontaneously hypertensive rats. Psychopharmacology 1986, 90: 170-172. PMID: 3097696, DOI: 10.1007/bf00181235.Peer-Reviewed Original Research
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