2019
Prenatal Inflammation Dampens Neurogenesis and Enhances Serotonin Transporter Expression in the Hippocampus of Adult Female Rats
Mouihate A, Kalakh S, AlMutairi R, Alashqar A. Prenatal Inflammation Dampens Neurogenesis and Enhances Serotonin Transporter Expression in the Hippocampus of Adult Female Rats. Medical Principles And Practice 2019, 28: 352-360. PMID: 30884483, PMCID: PMC6639577, DOI: 10.1159/000499658.Peer-Reviewed Original ResearchConceptsAnxiety-like behaviorPrenatal LPSAdult female ratsFemale ratsHippocampal neurogenesisSERT expressionSerotonin transporterFemale offspringGestational day 15Serotonin transporter expressionOpen field testPrenatal inflammationPregnant ratsAdult neurogenesisPrenatal exposureHippocampal expressionBACKGROUND/Adult offspringDay 15LPSNeurogenesisWestern blotTransporter expressionRatsHippocampus
2014
High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People
Kranz GS, Wadsak W, Kaufmann U, Savli M, Baldinger P, Gryglewski G, Haeusler D, Spies M, Mitterhauser M, Kasper S, Lanzenberger R. High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People. Biological Psychiatry 2014, 78: 525-533. PMID: 25497691, PMCID: PMC4585531, DOI: 10.1016/j.biopsych.2014.09.010.Peer-Reviewed Original ResearchConceptsSerotonin reuptake transporterSERT bindingFemale transsexualsStart of treatmentSteroid hormone treatmentNew treatment modalitiesTreatment of depressionMedian raphe nucleusHormone plasma levelsTreatment-induced increaseMid-cingulate cortexPositron emission tomographyMechanism of actionTreatment startSerotonergic transmissionEstradiol levelsRaphe nucleusEstrogen treatmentReuptake transporterTreatment modalitiesAndrogen treatmentEpidemiologic findingsPlasma levelsSex hormonesSERT expression
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