2015
Primary and secondary alterations of white matter connectivity in schizophrenia: A study on first-episode and chronic patients using whole-brain tractography-based analysis
Wu C, Hwang T, Chen Y, Hsu Y, Lo Y, Liu C, Hwu H, Liu C, Hsieh M, Chien Y, Chen C, Tseng W. Primary and secondary alterations of white matter connectivity in schizophrenia: A study on first-episode and chronic patients using whole-brain tractography-based analysis. Schizophrenia Research 2015, 169: 54-61. PMID: 26443482, DOI: 10.1016/j.schres.2015.09.023.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexBilateral DLPFCFirst-episode patientsWhite matter connectivityFirst-episodeChronic patientsBilateral dorsolateral prefrontal cortexFirst-episode schizophreniaWidespread white matter abnormalitiesBilateral temporal polesDebilitating mental disorderReduced white matter connectivityRight arcuate fasciculusSuperior longitudinal fasciculus IDuration of illnessAssociated with clinical variablesCallosal fibersBetween-group analysisWhite matter tractsWhite matter abnormalitiesPrefrontal cortexImpaired connectivityTemporal poleArcuate fasciculusCerebral white matter
2010
Preterm birth results in alterations in neural connectivity at age 16 years
Mullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years. NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingAge 16 yearsPT subjectsBrain injuryLow birth weight preterm childrenTerm controlsUncinate fasciculusBilateral external capsuleFA valuesWeight preterm childrenNeonatal brain injuryLower fractional anisotropy valuesYears of ageBilateral uncinate fasciculusFractional anisotropy valuesRight uncinate fasciculusRight arcuate fasciculusWhite matter disorganizationAlternative neural pathwaysPreterm birthExternal capsuleInferior frontal gyrusPreterm childrenCorpus callosumHigh risk
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