Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas in transgenic mice
Feldman B, Reid T, Cleary M. Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas in transgenic mice. Oncogene 1997, 15: 2735-2742. PMID: 9401000, DOI: 10.1038/sj.onc.1201670.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DivisionDisease ProgressionDNA Transposable ElementsGene RearrangementHomeodomain ProteinsLeukemia Virus, MurineLymphomaMiceMice, TransgenicMutagenesisNeoplasm TransplantationOncogene Proteins, FusionProtein Serine-Threonine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-pim-1RetroviridaeThymus NeoplasmsTransgenesConceptsTransgenic miceMonths of ageE2A-PBX1High-grade T-cell lymphomaE2A-PBX1 transgenic miceT-lineage lymphomasAssociated with tumor progressionT-cell lymphomaDevelopment of lymphomaSite of involvementRetroviral insertional mutagenesisLength of survivalActivated c-MycThymic lymphomasSyngeneic recipientsMonoclonal lymphomaTumor subpopulationsLymphomaTumor progressionRetroviral infectionGenetic eventsNegative cellsLymphomagenesisC-MycRetroviral insertion
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